Pentazocine Hydrochloride

Pentazocine Hydrochloride is a pain relieving medicine. It is used to manage persistent, moderate to severe chronic pain that requires continuous, around-the-clock treatment for an extended period of time. Pentazocine Hydrochloride is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), headache, drowsiness, fatigue, vomiting, constipation, dry mouth, and sweating. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using it, you should let your doctor know if you have problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Pentazocine Hydrochloride is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.

• Moderate to severe pain

Pentazocine is a benzomorphan derivative with mixed opioid agonist and antagonist actions. It alters perception of and response to pain and produces generalised CNS depression by binding to opiate receptors in the CNS and acting as a partial agonist/antagonist.

Adult Dose: Oral Moderate to severe pain Adult: 50-100 mg every 3-4 hrs; max 600 mg daily. Hepatic impairment: Reduce dose or avoid in liver disease. Child Dose: Oral Moderate to severe pain Child: 6-12 yr: 25 mg every 3-4 hr. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation 10-50 75% normal dose. <10 50% normal dose.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

If you miss a dose of Pentazocine Hydrochloride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Headache • Dizziness • Sleepiness • Vomiting • Nausea • Constipation

[UNSAFE] Pentazocine Hydrochloride may cause side effects which could affect your ability to drive. Pentazocine Hydrochloride may cause sedation especially if taken with alcohol. This may impair your driving ability. Use Pentazocine Hydrochloride as instructed by your doctor. Never take in greater amounts or more often than prescribed. It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery. Avoid consuming alcohol when taking the Pentazocine Hydrochloride, as it may cause excessive sleepiness or drowsiness. Inform your doctor if you have ever been diagnosed with kidney or liver problems. Store opioid pain relievers in a safe place and out of reach of others.

Head injury; narcotic dependence; respiratory depression; raised intracranial pressure; MI; heart failure; arterial or pulmonary hypertension; porphyria; pregnancy (prolonged use or high doses at term).

Depressant affects potentiated by alcohol, CNS depressants; concurrent use with fluoxetine may lead to diaphoresis, ataxia flushing and tremor associated with serotonin syndrome.

[UNSAFE] It is unsafe to consume alcohol with Pentazocine Hydrochloride.

[CONSULT YOUR DOCTOR] Pentazocine Hydrochloride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Pentazocine Hydrochloride is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Pentazocine Hydrochloride should be used with caution in patients with kidney disease. Dose adjustment of Pentazocine Hydrochloride may be needed. Please consult your doctor. [CAUTION] Pentazocine Hydrochloride should be used with caution in patients with liver disease. Dose adjustment of Pentazocine Hydrochloride may be needed. Please consult your doctor.

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