Generic
Saccharomyces Boulardii
10 brands available in the market
At a glance
Saccharomyces Boulardii is a probiotic used for the prevention and treatment of antibiotic-associated diarrhea, traveler's diarrhea, Clostridium difficile infection, IBS, and Crohn's disease. It acts as a temporary intestinal flora to protect gut health.
Description
Saccharomyces Boulardii is a live yeast that survives stomach acid and colonizes the intestinal tract as temporary flora. It exhibits antitoxin, antimicrobial, enzymatic, and immune-enhancing activities. It neutralizes C. difficile toxins, reduces pathogen adhesion, increases brush border enzyme activity, and stimulates protective IgA production.
Indications
- Antibiotic-associated diarrhea
- Traveler's diarrhea
- Clostridium difficile-associated diarrhea
- Helicobacter pylori treatment side effects
- Acute diarrhea
- Infant diarrhea
- Crohn's disease
- Ulcerative colitis and IBS
Therapeutic class
Herbal and Nutraceuticals
Pharmacological class
Probiotic
Pharmacology
Saccharomyces Boulardii acts as a temporary flora in the intestine. It neutralizes bacterial toxins, reduces pathogen adhesion to the intestinal wall, increases brush border enzyme activity, and stimulates the immune system by increasing protective IgA antibodies.
Mechanism of action
Prevents diarrhea by neutralizing toxins, reducing pathogen adhesion, and stimulating immunity.
Dosage
Adult Dose:
- Antibiotic-associated diarrhea: 250-500 mg 2-4 times daily
- C. difficile diarrhea: 1 g/day for 4 weeks with antibiotics
- Acute diarrhea: 250 mg twice daily for 5 days
- Crohn's disease: 250 mg 3 times daily (up to 9 weeks)
- IBS: 250 mg twice daily
- Traveler's diarrhea: 250 mg/day
Pediatric Dose:
- >3 months: 250 mg twice daily for 5 days
- <3 months: 125 mg twice daily for 5 days
Administration
- Take orally
- Take as directed by a physician
Missed dose
If you miss a dose, take it as soon as possible; if almost time for the next dose, skip it; do not double the dose.
Side effects
Side Effects:
- Gas (intestinal gas)
- Rare cases of abdominal discomfort
Precautions & warnings
- Safety in pregnancy and lactation not established; use with caution
- Avoid use with antifungal medications
Contraindications
- Hypersensitivity to Saccharomyces Boulardii or any component
Drug interactions
- Antifungal medications (fluconazole, itraconazole, terbinafine) reduce the effectiveness of Saccharomyces Boulardii
Food interactions
Caution is advised when consuming alcohol with Saccharomyces Boulardii; consult your doctor.
Use in pregnancy
Use in Pregnancy: Adequate safety information not available; consult your doctor.
Pregnancy Category: A — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Adequate safety information not available; consult your doctor.
Pediatric use
Indicated for infants and children
Geriatric use
Not applicable
Renal / hepatic impairment
Not applicable
Overdose effects
No overdose information available; consult your doctor if overused.
Storage conditions
Store below 25°C, away from direct sunlight and moisture; keep out of reach of children.
Chemical structure
Saccharomyces Boulardii