৳ 25/unit
Pack: ৳ 125
৳ 25/unit
Pack: ৳ 125
At a glance
Direct-acting sympathomimetic used in cardiac arrest, anaphylactic shock, and severe bronchospasm.
Indications
Adjunctive use in cardiac arrest management, anaphylactic reactions/shock, and life-threatening acute asthma.
Pharmacology
Exerts effect on both alpha and beta adrenoceptors. Increases systolic BP via vasoconstriction (alpha-1), increases heart rate and cardiac output (beta-1), and induces bronchodilation (beta-2).
Dosage
Cardiac arrest: 1 mg IV repeated every 2-3 min. Anaphylaxis/Asthma: Adult 0.25–0.5 mg repeated at 5-min intervals. Children: 10 mcg/kg initially (max 250 mcg).
Side effects
Anxiety, restlessness, dizziness, headache, palpitations, tachycardia, tremors, weakness, and coldness of extremities.
Use in pregnancy
Pregnancy Category C. Crosses the placenta; use only if potential benefit outweighs risk to the fetus.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Exercise extreme caution in elderly patients, coronary insufficiency, hypertension, diabetes, hyperthyroidism, and asthma with degenerative heart disease. Do not mix with sodium bicarbonate.
Overdose effects
Can cause cardiac arrhythmias, severe hypertension, pulmonary edema, and cerebral hemorrhage. Treat with combined alpha/beta-blockers (e.g., labetalol) or phentolamine.
Storage conditions
Store below 25°C. Protect from light and moisture. Keep out of reach of children.