AFM Plus

• Allergic and Inflammatory Eye Conditions: Used for acute and chronic conjunctivitis, keratitis, iridocyclitis, iritis, scleritis, episcleritis.
• Post-operative Infections: Used for prevention of infections after strabotomy, cataract and glaucoma surgery.

Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation. Gentamicin is an aminoglycoside that binds to 30S and 50S ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective.

Adult Dose (Ophthalmic):

• Bacterial infection (Suspension): 1 drop 5 times daily into conjunctival sac; severe cases: 1 drop per hour for 1-2 days.
• Post-operative infection (Suspension): 1 drop 4 times daily for 1 week; then reduced frequency.
• Bacterial infection (Ointment): Apply 3-4 times daily into the affected eye.
• Post-operative infection (Ointment): Apply before retiring to support suspension therapy.

Side Effects:

• Transient burning sensation after instillation
• Rare: Hypersensitivity reactions (eczema of eyelid, puncture keratitis)
• Prolonged use: Delayed wound healing, increased IOP, cataract formation, thinning of cornea and sclera

Use in Pregnancy: May be unsafe; consult your doctor.

Precautions:

• Steroids can mask, activate or aggravate ocular infections.
• Long term treatment with steroid may enhance thinning of cornea and sclera; rarely perforation reported.
• If no improvement after 7-8 days, other therapeutic means should be considered.
• Patients experiencing blurred vision after application should refrain from driving or operating machinery.
• Contact lenses should be removed before each application.

Overdose: Limited information on topical overdose; excessive use may cause eye irritation.

Storage: Store in a cool and dry place, protected from light. Keep out of reach of children.