Amiron 30
Rx- Generic:
- Mirtazapine
- Company:
- Orion Pharma Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 15/unit
Pack: ৳ 150
At a glance
Mirtazapine — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Mirtazapine is a prescription medicine used in the treatment of depression. This medicine helps by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relax the nerves, thus treating your depression. Mirtazapine may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly as it may worsen your symptoms. Some common side effects of this medicine include dryness in mouth, increased appetite, and headaches. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain; therefore, you should have a balanced diet and exercise regularly. Moreover, it is important to inform your doctor if you develop a sore throat or fever after taking this medicine. Mirtazapine is an antidepressant. It works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.
Indications
• Depression
Mechanism of action
Mirtazapine, a piperazinoazepine tetracyclic antidepressant, enhances noradrenergic and serotonergic activity through blockade of central presynaptic adrenergic alpha 2-receptors.
Dosage
Adult Dose: Oral Depression Adult: Initially, 15 mg daily; may be increased gradually depending on clinical response. Change dose at intervals of at least 1-2 wk. Usual effective dose: 15-45 mg daily given as single dose, preferably at bedtime, or in 2 divided doses. Elderly Depression 7.5 mg/day PO qHS; increase by 7.5-15 mg/day no more frequently than q1-2Weeks; not to exceed 45 mg/day Alzheimer Dementia-related Depression 7.5 mg/day PO qHS; increase by 7.5-15 mg/day no more frequently than q1-2Weeks; not to exceed 60 mg/day Hepatic impairment: Clearance is reduced; monitor closely Child Dose: Safety and efficacy not established Renal Dose: Renal impairment (CrCl <39 mL/min): Clearance is reduced; monitor closely
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mirtazapine may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Sleepiness • Dryness in mouth • Increased appetite • Headache • Weight gain
Precautions & warnings
[UNSAFE] Mirtazapine may cause side effects which could affect your ability to drive. Mirtazapine can affect your concentration or alertness. This may impair your driving ability. Mirtazapine starts to work more quickly than other antidepressants. Avoid driving or operating dangerous machinery as it may decrease alertness. Avoid consuming alcohol when taking the Mirtazapine, as it may cause excessive drowsiness and calmness. If your doctor asks you to stop Mirtazapine, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Notify your doctor immediately if you develop a sore throat or fever or stomatitis during treatment with Mirtazapine.
Contraindications
Mirtazapine Tablets are contraindicated in patients with a known hypersensitivity to mirtazapine or to any of the excipients.
Drug interactions
Potentiation of sedative effects with alcohol or benzodiazepines. Increased plasma levels with potent CYP3A4 inhibitors (e.g. HIV-protease inhibitors, azole antifungals including ketoconazole, erythromycin, nefazodone). Reduced plasma levels with carbamazepine and other inducers of CYP3A4. Increased bioavailability with cimetidine. Potentially Fatal: Do not use with or within 2 wk of stopping an MAOI; at least 1 wk should elapse between discontinuing mirtazapine and initiating any drug which may provoke a serious reaction (e.g. phenelzine).
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Mirtazapine.
Use in pregnancy
[CONSULT YOUR DOCTOR] Mirtazapine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Mirtazapine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. The baby should be monitored for behavioral side effects and adequate growth.
Renal / hepatic impairment
[CAUTION] Mirtazapine should be used with caution in patients with kidney disease. Dose adjustment of Mirtazapine may be needed. Please consult your doctor. [CAUTION] Mirtazapine should be used with caution in patients with liver disease. Dose adjustment of Mirtazapine may be needed. Please consult your doctor.
Common questions
Sir iam suffering from depression and insomania i am not comleting my night sleep this effect my hair my hairs are falling Get thyroid and b12 tested Tab Mirtaz. 7.5 mg at nite daily Hello sir you have advised me to take agoprex 25 to treat insomnia But sir it is not getting available in our town Please suggest another medicine like it Mirtaz 7.5 mg at nite I have tick tick sound in brain ,and infection of very minute pimples on my testoregion with blood clots on my lower part of leg and on foot, i am on antideprsents since 18 yrs I personally feel that there are some foreign particles in my blood stream which are creating all these things kindly guide me that which medicine I must take to eliminate all these things tab mirtaz 7.5 mg at nite At night when I sleep my thinking never stop and sleep disturbed many time at night. Due to that my next day get hamper. Please suggest Start tab Mirtaz 7.5. Mg at nite Insomnia since last six months. Get Thyroid tested Start Mirtaz 7.5 mg at nite I am suffering from insomnia and anxiety for last 60 days Many times I took Mirtaz 15 when i could not sleep and maintain it I could sleep by taking Mirtaz But next day i feel very dizzy and experience emotions of anger Can u plz help me to get rid of insomnia?? Mirtaz is not a sleeping pill, it's for treatment of depression. Insomnia can be a sign of depression. Please get a clinical evaluation done for the same by a qualified psychiatrist before taking treatment. Following link may help you understand sleep problems better- http://drjyotikapoor.com/2015/01/26/sleep-disorders/ I am diagnosed with bipolar disorder and depression since eight years. I am taking Dveniz 100 lithosun 800 mg luracid 80 mg modalert 200mg mirtaz 15 mg . But I am still not happy Resistance to medicines can be because of following factors- 1. Diagnostic confusion 2. Irregular treatment or lack of proper follow up with treating doctor 3. Inadequate dose of medicines 4. Pharmacodynamics/ pharmacokinetics 5. Internal biological resistance For Treatment Resistant Conditions, adjunctive measures like changing treatment goals, psychotherapy and ECTs can be tried I am confusing in my life in depression I have et the Petril plus Mirtaz 7. 5 But not solve problem Plz tel me happiness tips and teblet talk to clinical psychologist