Angitan Plus12.5mg+50mg
Rx- Company:
- Chemist Laboratories Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 1/unit
Pack: ৳ 1
At a glance
Hydrochlorothiazide + Losartan Potassium — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Hydrochlorothiazide + Losartan Potassium is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure. You can take Hydrochlorothiazide + Losartan Potassium with or without food. The dose will depend on your condition and how your respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase. The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhoea, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of hydrochlorothiazide and helps control your blood pressure. You may experience other possible side effects, but most are rare. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine. This medicine is not recommended during pregnancy and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects. Hydrochlorothiazide + Losartan Potassium is a combination of two medicines: Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively. Losartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.
Indications
• Hypertension (high blood pressure)
Mechanism of action
Hydrochlorothiazide increases renal excretion of sodium and chloride and reduces cardiac load. Losartan is an angiotensin II receptor (type AT1) antagonist antihypertensive which acts by blocking the actions of angiotensin II of renin-angiotensin-aldosterone system. The drug and its active metabolite selectively block the vasoconstrictor and aldosterone secreting effects of angiotensin II. The two drugs exert additive effects in hypertension.
Dosage
Adult Dose: Hypertension Initial: 50 mg/12.5 mg PO qDay If dose titrated upward, do not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO q12hr Decrease losartan to 25 mg PO qDay initially if volume depleted Child Dose: Safety and efficacy not established Renal Dose: Renal impairment CrCl 30 mL/min: No dosage adjustment required
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hydrochlorothiazide + Losartan Potassium may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Nausea • Taste change • Upset stomach • Diarrhea • Headache • Dizziness • Weakness • Decreased blood pressure • Increased blood uric acid • Increased blood lipid level • Glucose intolerance • Electrolyte imbalance
Precautions & warnings
[UNSAFE] Hydrochlorothiazide + Losartan Potassium may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Hydrochlorothiazide + Losartan Potassium for the treatment of high blood pressure. It can be taken with or without food. Hydrochlorothiazide + Losartan Potassium may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness. It may cause dizziness. Get up slowly when rising from a sitting or lying position. Use of Hydrochlorothiazide + Losartan Potassium during pregnancy or breastfeeding is unsafe. It may also decrease the risk of stroke and heart attacks.
Contraindications
Pregnancy, lactation; intravascular volume depletion.
Drug interactions
Reduced excretion of lithium; effect of diuretic, natriuretic & other antihypertensive w/ NSAIDs including selective COX-2 inhibitors. Do not co-administer w/ aliskiren in patients w/ diabetes & renal impairment. Losartan: Rifampin & fluconazole. Increased serum potassium w/ K-sparing diuretics (eg spironolactone, triamterene, amiloride), K supplements or salt substitutes containing K. Hydrochlorothiazide: Potentiate orthostatic hypotension w/ alcohol, barbiturates or narcotics. Antidiabetic drugs (oral agents, insulin), other antihypertensive drugs. Impaired absorption w/ cholestyramine & colestipol resins. Intensified electrolyte depletion w/ corticosteroids, ACTH, glycyrrhizin (liquorice). Possible decreased response to pressor amines (eg adrenaline); increased response to nondepolarizing skeletal muscle relaxants (eg tubocurarine). May interfere w/ parathyroid function test.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Hydrochlorothiazide + Losartan Potassium.
Use in pregnancy
[CONSULT YOUR DOCTOR] Hydrochlorothiazide + Losartan Potassium is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Hydrochlorothiazide + Losartan Potassium is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[CAUTION] Hydrochlorothiazide + Losartan Potassium should be used with caution in patients with severe kidney disease. Dose adjustment of Hydrochlorothiazide + Losartan Potassium may be needed. Please consult your doctor. Use of Hydrochlorothiazide + Losartan Potassium is not recommended in patients with severe kidney disease. [CAUTION] Hydrochlorothiazide + Losartan Potassium should be used with caution in patients with liver disease. Dose adjustment of Hydrochlorothiazide + Losartan Potassium may be needed. Please consult your doctor.
Common questions
Stunting done in 2011. All reports including echo are coming normal since then. One medicine cardiac H or remipril is shooting cough. What substitute I can take which can fix cough.? Stop ramipril start losar h 25/12.5 For hypertension I had used RevasAM5 for last 5 years. But from it is shown that B.P 170/90. From From I used Telma80, but till date B.P is 170/100. What medicine I should used? Adv-low salt diet Do- KFT,ECG,lipid profile Take Tab Losar-H 1OD( morning Tab Amlovas 5MG 1OD(evening) Why blackish red & small white spot my mother skin( leg & hand upper part) Only hi blood pressure problems Medicine. Is losar H Can continue ur BP Treatment BP is 190/90, i hv given losar 25 two teblates, pls suggest Need to find cause for hypertensionPlease send physician near u for proper examination and blood work up I take losar H tab twice a day i feel giddiness what shoul i do get your BP monitored by a Doctor I have 110-170 blood pressure,sugar fasting100,cholostrol normal ,but now l have very high headache with pain only one side(left) whatever medicine u taking for BP stop that and take ramistar H once daily I am using Losar H for Blood pressure. I find this effect Kidney. At present my urine colour sometimes it looks reddish. So may I continue or use some other medicine. My blood pressure remain 140/ 85 generally Need to further investigate visit physician near by or our clinic at sector 31 house 1298 Grace dental and medical clinic Gurgaon Suffering from hypertension prescribed zyltan 50mg 6 years ago and it was good. But now the tablet is not available. hence I wnt to doctor again and he prescribed NEWTEL H 40. but if I take this tab causing headache and pain in neck and shoulder. Please suggest some alternative. Is there any way to get rid of hypertension permanently. There is no permanent treatmentYou have to take medicineEat less salt in dietTab LOSAR 50MG TAB LOSAGARD 50MGEither of above medicine