Ariproct
Rx৳ 70/unit
Pack: ৳ 70
৳ 70/unit
Pack: ৳ 70
At a glance
Cinchocaine Hydrochloride 0.5% + Esculin 1% + Hydrocortisone + Neomycin Sulphate is a combination medicine used for the treatment of pruritus ani, haemorrhoids, anal fissure, and proctitis.
Indications
- Pruritus ani
- Haemorrhoids
- Anal fissure
- Proctitis
Pharmacology
Cinchocaine prevents or diminishes nerve impulse conduction near to the site of administration. It also has membrane-stabilising effect owing to decrease of permeability of the nerve cell to sodium ions. Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. Neomycin is an aminoglycoside antibiotic. It binds to 30S ribosomal subunits of bacterial ribosome thus inhibiting protein synthesis and generating errors in genetic code transcription causing cell death. Esculin improves skin vasculature and is effective in the management of cellulitis.
Dosage
Adult Dose (Ointment): Apply onto the affected area in the morning and evening and after each stool.
Adult Dose (Suppository): Insert 1 suppository in the morning and evening and after each stool.
Side effects
Common Side Effects:
- Restlessness
- Excitement, nervousness
- Paraesthesias
- Dizziness
- Tinnitus
- Blurred vision
- Nausea, vomiting
- Muscle twitching, tremors
- Convulsions
- Hypotension
- Bradycardia
- Arrhythmias
- Cardiac arrest
Use in pregnancy
Limited information is available regarding use during pregnancy. Avoid application for prolonged periods and to extensive areas. Consult your doctor.
Precautions & warnings
- Elderly, debilitated patients, children, epilepsy, impaired cardiac conduction or respiratory function, shock, hepatic impairment, myasthenia gravis require caution.
- Do not rub or touch the eye while anaesthesia persists.
- Avoid application for prolonged periods and to extensive areas.
- Caution during pregnancy and lactation.
Overdose effects
Information on overdosage is not available. Consult a physician if overdose is suspected.
Storage conditions
Store in a cool and dry place, protected from light. Keep out of reach of children.