Becosules

• Deficiencies of, or increased requirement for, vitamin B-complex and vitamin C
• Decreased intake because of restricted or unbalanced diet (anorexia, diabetes mellitus, obesity, alcoholism)
• Reduced availability during treatment with antimicrobials
• Increased requirements due to increased metabolic rate (fever, acute or chronic infections, surgery, burns, fractures)
• Stomatitis, glossitis, cheilosis, paraesthesias, neuralgia, dermatitis
• Micronutrient deficiencies during pregnancy or lactation

Adult Dose (Oral):

• One capsule daily or as advised by the physician

Adult Dose (Injection):

• One vial (10 ml) daily

Child Dose (11 years and above) (Oral):

• 1-2 capsules daily

Child Dose (11 years and above) (Injection):

• One vial (10 ml) daily

Children below 11 years of age:

• Children weighing less than 10 kg should be given 1 ml of the dissolved mixture per kg body weight/day
• Children weighing 10 kg or more should be given 10 ml (one vial) of the dissolved mixture/day

Common Side Effects:

• The unwanted effects of nutrient solutions are a rise in the body temperature, shivering, chills and nausea and vomiting
• Allergic reactions (including anaphylaxis)
• Dermatological reactions (flushing, erythema, pruritus)
• CNS reactions (headache, dizziness, agitation)

• Folic acid may mask the symptoms of pernicious anemia
• In patients receiving TPN, routine supplementation with both fat-soluble and water-soluble vitamins is recommended
• Daily vitamin requirements must be calculated to avoid over dosage and toxic effects, especially with regards to vitamins A & D and particularly in pediatric patients
• In patients for whom TPN is continued for prolonged periods, periodic monitoring of blood vitamin levels should be considered
• To prevent excessive excretion of water-soluble vitamins, daily dosage should be administered over a number of hours