Benzapen 12 Lac12LacUnit
Rx- Generic:
- Benzathine Penicillin
- Company:
- Square Pharmaceuticals PLC.
- Dosage form:
- Injection
- Pack size:
- Injection
৳ 30/unit
Pack: ৳ 30
At a glance
Benzathine Penicillin — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Benzathine Penicillin is an antibiotic used to treat a variety of bacterial infections. It is effective in treating sore throat and sexually transmitted diseases like Syphilis. This medicine is also used to prevent some bacterial infections such as Rheumatic fever. Benzathine Penicillin is a long-acting type of penicillin, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as an injection into the muscle under the supervision of a healthcare professional. It should be used regularly as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication. Before taking this medicine, inform your doctor if you are allergic to penicillin or any penicillin-type of medicine. Rash, allergic reactions or pain, swelling, and redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor's supervision. Benzathine Penicillin is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
Indications
• Bacterial infections • Syphilis • Prevention of rheumatic fever
Mechanism of action
Benzathine benzylpenicillin has the same antimicrobial action as benzylpenicillin which exerts its bactericidal action on growing and dividing bacteria by inhibiting bacterial cell wall synthesis. IM admin results in a prolonged effect, but because of its relatively low blood concentrations, its use should be restricted to microorganisms that are highly susceptible to it.
Dosage
Adult Dose: Adult: IM: 0.3 to 1.2 million units up to 2.4 million units as a single dose repeated every five to seven days. Specific dosage schedule: Treatment of group-A beta-haemolytic streptococcal infections: A single intramuscular dose of 600,000 units. Prevention of rheumatic fever: Monthly injection of a single dose of 1.2 million units is the most effective regimen for preventing further attacks of rheumatic fever. Treatment of acute otitis media: A single injection of 600,000 units. Treatment of syphilis: Early syphilis- 2.4 million units as a single dose. Late syphilis- 2.4 million units weekly for three successive weeks. Neurosyphilis- Benzylpenicillin, intravenously, 2 to 4 million units every 4 hours for 10 days, followed by benzathine penicillin intramuscularly, 2.4 million units weekly for three successive weeks. Congenital syphilis: Asymptomatic infants with normal cerebrospinal fluid, intramuscularly 50,000 units per kg in a single dose. Primary and secondary syphilis have been treated with single injections of 2.4 million units of long acting benzathine penicillin (Benzapen) weekly for 2 to 4 weeks with satisfactory results. Child Dose: Child: IM 50,000 U/kg for newborns and infants, Child: IM 50,000 U/kg for newborns and infants, children 60 lb: 900,000 U 1 dose for treatment
Administration
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Side effects
Common: • Rash • Allergic reaction • Injection site reactions (pain, swelling, redness)
Precautions & warnings
[UNSAFE] Benzathine Penicillin may cause side effects which could affect your ability to drive. You have been prescribed Penidure LA 12 Injection for the treatment of bacterial infections. It is given by an injection into a vein or muscle, or via a drip into a vein. Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Contraindications
Hypersensitivity to penicillins or cephalosporins. IM inj (ischaemic reactions may occur).
Drug interactions
Probenecid prolongs T1/2 of benzathine benzylpenicillin. Bacteriostatic drugs e.g. chloramphenicol, tetracyclines; other antibacterials; anticoagulants.
Food interactions
[SAFE] Consuming alcohol with Benzathine Penicillin does not cause any harmful side effects.
Use in pregnancy
[SAFE IF PRESCRIBED] Benzathine Penicillin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Benzathine Penicillin is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Renal / hepatic impairment
[CAUTION] Benzathine Penicillin should be used with caution in patients with kidney disease. Dose adjustment of Benzathine Penicillin may be needed. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Benzathine Penicillin in patients with liver disease. Please consult your doctor.
Common questions
I had PBMV 10 years back from post PBMV iam taking a dosage of penidure 12lac injection for every 21 days is thare any alternate for the injection as i am going to abroad it's difficult to take injection in abroad please suggest me a alternate. U can get same thereOr available in oral form too tab pentids My child is. Suffering. Fevers. From. 1day. There. Is. No. Effect. Of. Perecitamal. We. Have. Given. Him. Biogesic/ ap. Now. He. Didn't. Have. Any. Fever. It. Is. Important. To. Give. Entibitic. To. Him Hello, generally antibiotics are not needed for fever control unless having obvious signs of bacterial infections on examination. My child verry high cough and fever in cold sesion try to much doctor but result is no . It's will be countiue cough and fever it's good to be only antiboitic Antibiotics are required if bacterial infections. Consult child specialist I have joint pain since 8 - 9 yrs But doctors prescribe pented 8 lacs Whats matter Doctor says u hv Heart problems Before pented 8 lacs Used penideore 12 lack injection Plz suggects sir Doctor might be treating , thinking that you have Rheumatic arthritis, you send your all investigation reports, & all your problems. ASO Titre is bit higher than normal. Shall I have to be worried for that much ASO titer determination can help distinguish beta-hemolytic Group A Streptococcal rheumatic fever from acute rheumatic diseases.Get done rheumatoid factor test I have a history of recurring yeast and bacterial vaginosis infections. Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days Scar on face due to bacterial infections Pic is not clear, plz visit for proper opinion I m a AVR patient and take acitrom tablet regularly with penidure LA 12 injection in every 21 days since last 2008 June. I just want to know that how long I shall be take these medicines in my life and what should be eaten by me and what should avoid by me ? Pls advise me sir Sir pls advise me how my life style is maintain by me in day to day life. What should be done and at which level Medicines will be lifelong