৳ 500/unit
Pack: ৳ 500
৳ 500/unit
Pack: ৳ 500
At a glance
Bimatoprost 0.03% + Timolol 0.5% Eye Prep is a combination medicine used in the treatment of ocular hypertension and glaucoma. It works by decreasing the production of aqueous humour (fluid in the eye), thereby lowering increased eye pressure.
Indications
- Open-angle glaucoma
- Ocular hypertension
- Reduction of intraocular pressure in patients insufficiently responsive to monotherapy
Pharmacology
Bimatoprost lowers IOP by increasing aqueous humor outflow through both the trabecular meshwork and uveoscleral routes. It mimics the action of a naturally-occurring prostaglandin, increasing the drainage of aqueous humour out of the eyeball, and may also lower the rate of aqueous formation. Timolol is a non-selective beta-adrenergic receptor antagonist that reduces elevated as well as normal intraocular pressure by decreasing aqueous humor production.
Dosage
Adults: One drop in the affected eye(s) once daily.
Children: Safety and effectiveness in pediatric patients have not been established.
Elderly: No overall differences in safety or effectiveness have been observed between elderly and other adult patients.
Side effects
Common (in clinical trials):
Ocular hyperemia (approximately 26% of patients), decreased visual acuity, eye discomfort, foreign body sensation, eye pain, pruritus (itching), stinging sensation, burning sensation.
Other:
Darkening of eyelashes (temporary), change in iris color (brown pigmentation with long-term use), eye redness.
Use in pregnancy
May be unsafe during pregnancy. Limited human studies available; animal studies have shown harmful effects on the developing baby. Should not be used during pregnancy unless clearly necessary. Consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- May cause short-term blurring of vision after use; do not drive or use machinery until vision is clear.
- Apply pressure on the corner of the eye (close to the nose) for about 1 minute immediately after instilling the drop.
- Use within 4 weeks of opening the bottle.
- May cause eyelashes to grow longer, darker, and thicker (not harmful).
- May cause brown pigmentation of the iris with long-term use (permanent but not harmful).
- Caution in patients with cardiovascular disease or pulmonary disorders (due to systemic absorption of timolol).
Overdose effects
Overuse may cause eye irritation, redness, or systemic beta-blocker effects (bradycardia, hypotension). Consult your doctor if symptoms occur.
Storage conditions
Store below 25°C in a dry place protected from light. Keep out of reach of children. Solution can be used up to 28 days after first opening.