Binzotim1%+0.5%
Rx- Generic:
- Brinzolamide + Timolol eye prep
- Company:
- Eskayef
- Dosage form:
- Eye Drop
- Pack size:
- 5ml bot
৳ 550/unit
Pack: ৳ 550
At a glance
Brinzolamide + Timolol eye prep — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Brinzolamide + Timolol eye prep is a prescription medicine having a combination of medicines that is used to treat pressure in the eyes (ocular hypertension) and glaucoma. It works by decreasing the pressure of fluid in the eye (aqueous humor), which helps in lowering the increased eye pressure. Brinzolamide + Timolol eye prep is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The most common side effects include irritation and burning sensation at the application site. If these side effects persist for a longer duration, inform your doctor. In case by accident, this medicine goes into your ears, nose or mouth, immediately rinse it with water. Inform your doctor if you are pregnant or breastfeeding or are allergic to this medicine or taking any other medication. It is advised not to drive or operate heavy machinery after use of this medicine as it may cause blurring of vision and may affect your ability to drive. Brinzolamide + Timolol eye prep is a combination of two medicines: Brinzolamide and Timolol. Brinzolamide is a carbonic anhydrase inhibitor while Timolol is a beta blocker. They work by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.
Indications
• Ocular hypertension • Glaucoma
Mechanism of action
Brinzolamide is a carbonic anhydrase inhibitor that decreases secretion of aqueous humor thus reducing intraocular pressure. Exact mechanism of ocular hypotensive effect is unclear, but it is thought to be related to reduction of aqueous humour formation. beta-blockade also causes lowering of BP.
Dosage
Adult Dose: 1 drop into the affected eye(s) twice daily.
Administration
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
Side effects
Common: • Itching • Irritation • Stinging sensation • Burning sensation in eye • Blurred vision • Eye redness • Taste change
Precautions & warnings
[UNSAFE] Brinzolamide + Timolol eye prep may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear. Brinzolamide + Timolol eye prep is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss. Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop. If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in. Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops. Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution. It may cause short term blurring of vision when first used. Use caution before driving or using machines. It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away. Make sure to use within 4 weeks of opening the bottle.
Contraindications
Bronchial asthma, severe COPD, sinus bradycardia, 2nd or 3rd degree AV block, overt cardiac failure, cardiogenic shock, severe allergic rhinitis, bronchial hyperreactivity, hyperchloraemic acidosis, severe renal impairment.
Drug interactions
Brinzolamide: Concurrent use w/ oral carbonic anhydrase inhibitors may lead to additive systemic effects. Concurrent use w/ high-dose salicylates may lead to toxicity. Timolol: Concomitant admin w/ reserpine may increase hypotension and bradycardia. Additive effects w/ other antihypertensives (e.g. hydralazine, methyldopa). Increased ?-adrenergic blockade (e.g. decreased heart rate) w/ quinidine. Rebound HTN due to abrupt withdrawal of clonidine. Hypotensive effect may be antagonised by NSAIDs (e.g. indomethacin, ibuprofen).
Food interactions
No interaction found/established
Use in pregnancy
[CONSULT YOUR DOCTOR] Brinzolamide + Timolol eye prep may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Brinzolamide + Timolol eye prep is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
No interaction found/established No interaction found/established
Common questions
Doctor advised for medication for glaucoma suspect only because eye pressure is 22 but all other tests are normal.medicine , 9 pm drops is prescribed. Please advice Ocular hypertension can lead to glaucoma eventually. Continue the drops I have been taking Timolet OD drops everyday for the last three months to help with high ocular pressure. Lately I have been feeling opaqueness in vision. Visit glaucoma specialist for eye examination I have eye pressure about 5 years my right eye 95 portion spoil and left eye good but in pressure so what about to do doctor? My drop is travo prost timo ceinT please do some to me U have to instill the drops. . As glaucoma can only be controlled not cured. Visit glaucoma specialist Plz subscribe a drop fr cataract eye wth glucoma In present using bidin lstm fr glucoma Cataract should be operated. Glaucoma? medicine should be continued as such Golucoma in eye pain in eye both Glaucoma needs prompt treatment Visit glaucoma specialist eye pressure 26 , tireness of eyes when working on computer, feeling uneasy , burning sensation and pain in eyes. have done cataract lasik surgery two month back. consulted eye specilist at ambala suggested eye drop dorzox T 5ML.Got some relief but not fully cured . advice whether continue dorzox U need examination by glaucoma specialist and need further investigation I am looking for I kul plus eye drop but i am not able to get in Banglore suggest Me some eye drop for that my eyes become red so remove that redness I want this drop One of chemist suggest me tears plus drop is this substitute of I kul plus please give on eye drop name for I become red now my I become red as blood These are my right eye prescription but after using these drop my eyes is still red so normally I was using I kul plus but now it's not in supply can please give me any substitute for that Seems u r having glaucoma. Using these drops may a Also cause redness. Or raised iOp can also cause it. Again go for eye checkup by Eye pressure since 2 years. Diabetic patient.timilol eye drops using.remedy pls Glaucoma once occurs shd be treated life long. Visit glaucoma specialist