Biotric Adapalene & Clindamycin Gel – Advanced Acne Treatment & Skin Clarifying

Used for the treatment of acne vulgaris

Adapalene is a retinoid that normalizes skin cell turnover and prevents comedone formation. Clindamycin Phosphate is an antibiotic that kills acne-causing bacteria (Propionibacterium acnes) by inhibiting bacterial protein synthesis .

Adults and children over 12 years: Apply a thin layer to clean, dry skin once daily at night . During the first week of treatment, acne may worsen (initial exacerbation), which is normal. Therapeutic effect is observed 8-12 weeks after starting treatment

Common Side Effects: • Redness (Erythema) • Peeling • Dryness • Itching (Pruritus) • Burning or stinging sensation • Application site irritation Serious Side Effects (Rare – Consult Doctor): • Allergic reactions (Anaphylaxis, Angioedema, Urticaria) • Diarrhea • Bloody diarrhea • Colitis (including pseudomembranous colitis) • Severe skin irritation or contact dermatitis

Available data with this combination in pregnant women are insufficient. Clindamycin has not been associated with major birth defects. Adapalene animal studies at high oral doses showed fetal malformations . Use during pregnancy only if clearly needed and with medical advice.

Avoid contact with eyes, lips, areas of the nose, and mucous membranes . Do not apply to eczematous skin lesions, sunburns, cuts, or other skin lesions . Avoid excessive sunlight and UV light (tanning beds, sun lamps) during treatment due to increased skin sensitivity . Contraindicated in patients with a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis . Discontinue use if significant diarrhea occurs . Consult your doctor during pregnancy and breastfeeding.

Possible redness and peeling of the skin when excessive amounts of gel are applied. Therapy is symptomati

Store below 30°C, protected from light. Keep out of reach of children. Do not use after the expiry date.