৳ 10.03/unit
Pack: ৳ 210.63
৳ 10.03/unit
Pack: ৳ 210.63
At a glance
Butamirate Citrate is a centrally acting cough suppressant (antitussive) used in the treatment of dry (non-productive) cough, whooping cough, and pre- and post-operative cough. It works by directly acting on the cough center in the brain to suppress the cough reflex.
Indications
- Dry (non-productive) cough
- Whooping cough
- Pre- and post-operative cough
- Sedation prior to bronchoscopy and surgical procedures
- Cough due to acute lower respiratory tract infections (tracheitis, laryngitis, bronchitis)
Pharmacology
Butamirate Citrate is a centrally acting cough suppressant not related to opium alkaloids. It acts directly on the cough center in the brain to suppress the cough reflex. It is rapidly and completely absorbed after oral administration (maximum concentration reached within 9 hours with sustained-release tablets), highly protein-bound, and has a plasma elimination half-life of about 13 hours. Its active metabolites also have antitussive action.
Dosage
Adults (Tablet 50 mg): 2-3 tablets daily (at 8-12 hour intervals).
Adults (Syrup): 15 ml 4 times daily.
Adolescents (>12 years, Tablet): 1-2 tablets daily.
Adolescents (Syrup): 15 ml 3 times daily.
Children (6-12 years, Syrup): 10 ml 3 times daily.
Children (3-6 years, Syrup): 5 ml 3 times daily.
Infants (2 months-1 year, Pediatric Drops): 0.50 ml (10 drops) 4 times daily.
Infants (1-3 years, Pediatric Drops): 0.75 ml (15 drops) 4 times daily.
Note: Consult a doctor if cough persists for more than 7 days (or more than 3 days in children under 12 years).
Side effects
Butamirate Citrate is generally well tolerated. In rare cases, the following side effects may occur:
• Skin rash
• Nausea
• Diarrhoea
• Dizziness/Vertigo
These reactions usually resolve after dose reduction or treatment withdrawal.
Use in pregnancy
Do not use during the first trimester of pregnancy. May be used during the second and third trimesters with caution and under medical supervision.
Precautions & warnings
- Avoid concomitant use with expectorants (may lead to mucus retention in the airways, increasing risk of bronchospasm and respiratory infections).
- Do not use during the first trimester of pregnancy; use with caution during the second and third trimesters.
- Consider the benefits and risks during breastfeeding.
- Consult a doctor if cough persists for more than 7 days (or more than 3 days in children under 12 years).
Overdose effects
Overdose symptoms: Drowsiness, nausea, vomiting, diarrhea, loss of balance, hypotension. Standard emergency procedures: activated charcoal, saline laxatives, and standard cardio-respiratory resuscitation.
Storage conditions
Keep away from light and moisture, store below 30°C. Keep out of reach of children.