৳ 200/unit
Pack: ৳ 200
৳ 200/unit
Pack: ৳ 200
At a glance
Lornoxicam is a non-steroidal anti-inflammatory drug (NSAID) used for short-term relief of acute mild to moderate pain and symptomatic relief of pain and inflammation in osteoarthritis and rheumatoid arthritis.
Indications
- Short-term relief of acute mild to moderate pain
- Symptomatic relief of pain and inflammation in osteoarthritis
- Symptomatic relief of pain and inflammation in rheumatoid arthritis
Pharmacology
Lornoxicam inhibits cyclooxygenase enzyme to prevent prostaglandin synthesis, leading to desensitization of peripheral nociceptors and inhibition of inflammation.
Dosage
Acute Pain: 8-16 mg/day in 2-3 divided doses; max 16 mg/day
Osteoarthritis & Rheumatoid Arthritis: Initial 12 mg/day in 2-3 divided doses; maintenance max 16 mg/day
Renal/Hepatic Impairment (Mild-Moderate): Max 12 mg/day in 2-3 divided doses
Side effects
Common Side Effects:
- Nausea
- Vomiting
- Diarrhea
- Flatulence
- Constipation
- Dyspepsia
- Abdominal pain
- Melena
- Hematemesis
- Peptic ulcer
- GI bleeding (rare, especially in elderly)
Use in pregnancy
Use in Pregnancy: No data in first and second trimesters; contraindicated in third trimester; should not be used during delivery.
Precautions & warnings
- Caution in patients with history of peptic ulcer or GI bleeding
- Caution in patients with impaired kidney function, history of hypertension or heart failure
- Caution in ulcerative colitis or Crohn's disease
- Caution in patients with history of bleeding tendency or asthma
- Caution in patients with SLE (Systemic Lupus Erythematosus)
Overdose effects
No overdose experience; nausea, vomiting, cerebral symptoms (dizziness, vision disturbances) may occur; gastric lavage; not dialyzable.
Storage conditions
Store below 30°C, away from light and moisture; keep out of reach of children.