৳ 4.50/unit
Pack: ৳ 45
৳ 4.50/unit
Pack: ৳ 45
At a glance
Celecoxib is a pain relieving medicine used to alleviate pain, redness, and swelling in conditions such as osteoarthritis, rheumatoid arthritis, and pain during menstruation.
Indications
- Osteoarthritis
- Rheumatoid Arthritis
- Dysmenorrhea (Pain during menstruation)
- Pain Relief
- Ankylosing Spondylitis
- Juvenile Idiopathic Arthritis
Pharmacology
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor primarily responsible to reduce mediators of pain and inflammation. Its action is due to inhibition of prostaglandin synthesis via inhibition of COX-2.
Dosage
Adult Dose (Oral):
| Condition | Dose | Schedule |
|---|---|---|
| Osteoarthritis | 200 mg/day | Single or 2 divided doses; may increase to 200 mg twice daily if needed |
| Rheumatoid Arthritis | 100-200 mg | Twice daily |
| Dysmenorrhea/Pain Relief | Initial: 400 mg, then 200 mg (Day 1); Maintenance: 200 mg | Twice daily |
| Ankylosing Spondylitis | Initial: 200 mg/day; may increase to 400 mg/day after 6 weeks | Single or 2 divided doses |
Pediatric Dose: Juvenile Idiopathic Arthritis (>2 years, 10-25 kg): 100 mg twice daily.
Hepatic Dose: Moderate (Child-Pugh B): Reduce dose by 50%. Severe (Child-Pugh C or ≥10 score): Contraindicated.
Side effects
Common Side Effects:
- Stomach pain
- Diarrhea
- Flatulence
- Flu-like symptoms
- Peripheral edema
- Dizziness
- Indigestion
Use in pregnancy
[CONSULT YOUR DOCTOR] Celecoxib is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. Pregnancy Category D.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- [UNSAFE] Celecoxib may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
- Celecoxib helps relieve pain and inflammation. It may cause fewer stomach problems as compared to other NSAIDs like Ibuprofen or Naproxen.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Do not consume alcohol while on treatment with this medicine as it may cause excessive drowsiness.
- Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
- Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
- During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
- Do not take Celecoxib if you are pregnant, planning to conceive, or breastfeeding.
Overdose effects
Information on Celecoxib overdosage is not available. In case of overdose, symptomatic and supportive treatment should be given.
Storage conditions
Store below 30°C, protected from light and moisture. Keep out of the reach of children.