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At a glance

Clindamycin 2% Vaginal prep is a combination medicine used for the treatment of vaginal infections associated with vaginal discharge.

Indications
  • Syndromic treatment of vaginal discharge
  • Bacterial vaginosis
Pharmacology

Clindamycin inhibits protein synthesis by reversibly binding to the 50S subunit of the ribosomal, thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth. Clotrimazole works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane.

Dosage

Adult Dose (Bacterial Vaginosis): Nonpregnant patients: 1 full applicator (approximately 5 grams) intravaginally at bedtime for 3 days. Pregnant patients: 1 full applicator at bedtime for 7 days.

Pediatric Dose (<12 years): Safety and efficacy have not been established.

Side effects

Common Side Effects:

  • Vaginal burning sensation
  • Itching
  • Irritation
  • Stinging at the application site
Use in pregnancy

[SAFE IF PRESCRIBED] Clindamycin 2% Vaginal prep is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Pregnancy Category B.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • This medicine is inserted into the vagina using an applicator, usually at night before going to bed.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Avoid contact with your eyes. If accidental exposure occurs, rinse immediately with plenty of water.
  • It can damage condoms and diaphragms and make them ineffective at preventing pregnancy. Ask your doctor about other suitable methods of preventing pregnancy.
  • Inform your doctor if your symptoms do not get improved within 3 days of taking the medicine.
  • Contraindicated in individuals with a history of regional enteritis, ulcerative colitis, or a history of "antibiotic-associated" colitis.
Overdose effects

Excessive application may result in severe irritation. Discontinue use and wait until the skin has recovered. In the event of accidental ingestion, gastrointestinal adverse reactions similar to those seen with systemically administered clindamycin may be seen.

Storage conditions

Store in a cool and dry place, away from light and out of reach of children.

Clindamycin 2% Vaginal prep — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.