Combipres0.2%+0.5%

Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep is a prescription that is used for the treatment of pressure in the eyes (ocular hypertension) and glaucoma. It works by decreasing the pressure of fluid in the eye (aqueous humor), which helps in lowering the increased eye pressure. Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The most common side effects include irritation, redness and burning sensation at the application site. If these side effects persist for a longer duration, inform your doctor. In case by accident, this medicine goes into your ears, nose or mouth, immediately rinse it with water. Inform your doctor if you are pregnant or breastfeeding or are allergic to this medicine or taking any other medication. It is advised not to drive or operate heavy machinery after use of this medicine as it may cause blurring of vision and may affect your ability to drive. Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep is a combination of two medicines: Timolol and Brimonidine. Timolol is a beta blocker while Brimonidine is a sympathomimetic. They work by decreasing the production of aqueous humor (fluid in the eye), thereby lowering the increased eye pressure.

• Ocular hypertension • Glaucoma

Brimonidine is an alpha 2-adrenoceptor agonist which works to reduce aqueous humor production and increase uveoscleral flow. Timolol is a non-selective beta-adrenergic receptor blocker. It does not have significant intrinsic sympathomimetic activity, direct myocardial depressant activity or local anaesth activity. Exact mechanism of ocular hypotensive effect is unclear, but it is thought to be related to reduction of aqueous humour formation. beta-blockade also causes lowering of BP.

Adult Dose: Adult: Ophth: Instill 1 drop 2 times/day approximately 12 hours apart.

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

Common: • Itching • Stinging sensation • Foreign body sensation • Burning sensation in eye • Eye redness • Blurred vision • Tiredness • Drowsiness • Headache • Dryness in mouth

[UNSAFE] Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep may cause side effects which could affect your ability to drive. Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep may cause blurred or abnormal vision. This effect may seem worse at night or in reduced lighting and this may affect the ability to drive. Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss. Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop. If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in. Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops. Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution. It may cause short term blurring of vision when first used. Use caution before driving or using machines. It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away. Make sure to use within 4 weeks of opening the bottle.

Hypersensitivity. Patients receiving MAO inhibitor therapy.

Brimonidine Tartrate: Possibility of an additive or potentiating effect with CNS depressants e.g. alcohol, barbiturates, opiates, sedatives or anaesthetics. Caution when used with ?-blockers (ophthalmic and systemic), antihypertensives or cardiac glycosides. TCAs can affect the metabolism and uptake of circulating amines. Timolol: Concomitant admin w/ reserpine may increase hypotension and bradycardia. Additive effects w/ other antihypertensives (e.g. hydralazine, methyldopa). Increased ?-adrenergic blockade (e.g. decreased heart rate) w/ quinidine. Rebound HTN due to abrupt withdrawal of clonidine. Hypotensive effect may be antagonised by NSAIDs (e.g. indomethacin, ibuprofen).

No interaction found/established

[CONSULT YOUR DOCTOR] Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. To reduce the amount of Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep that reaches the breastmilk, place pressure over the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

No interaction found/established No interaction found/established

Doctor advised for medication for glaucoma suspect only because eye pressure is 22 but all other tests are normal.medicine , 9 pm drops is prescribed. Please advice Ocular hypertension can lead to glaucoma eventually. Continue the drops Suffering from glaucoma for past 2 years.applying combigan and xalatan as per doctor s advice. Any other permanent remedy Continue drops and donot stop. No other remedy there is a medicine prescribed by a doctor , but i can't understand the name of that medicine i am sending the image as attached prescription. There are 6 medicines in prescriptionTravatan, combigan, iopar SR , xalatan, alpha gan P, dorzox T I have been taking Timolet OD drops everyday for the last three months to help with high ocular pressure. Lately I have been feeling opaqueness in vision. Visit glaucoma specialist for eye examination PROBLEM - RED EYE WITH ITCHING PROBLEM. USING OFLOXACIN OPHTHALMIC SOLUTION IP (OFLOX) EYE DROP SINCE THREE DAYS BUT NOT GETTING RELIEF Consult an eye specialist I have Glacoma problem in my both eyes. What's the permanent solution As per doctors advice I'm use eye drops of Misopot , Latoprost RT Dear Doctor, Above. I attached my Prescription of Glacoma problem in my both eyes. This issue declared by Arivind Eye hospital, Madurai. As per doctors advice I want use this drops in my End of life. Kindly give me permanent solution of this problem Pls do needful Glaucoma needs life long treatment. No other solution. Get your intraocular pressures checked regularly and don't forget to put the drops. Solution of blood prashant and resin of bp What resin of bp and solution Mostly renal cause in younger patients n most ly essential hypertension in elderly I am suffering from eye syte last 2-3 days and i am using ofloxacin ophthalmic solution ip provide by gov doctor. if its infective, you may need oral antibiotics. review with your doctor for the same