oshudhkosh

Coversyl Plus4mg+1.25mg

Rx
Dosage form:
Tablet
Pack size:
Box (30 Tablet)

৳ 23/unit

Pack: ৳ 690

At a glance

Indapamide + Perindopril Erbumine — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Indapamide + Perindopril Erbumine is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce the chances of any future heart attack and stroke. Indapamide + Perindopril Erbumine should be taken on empty stomach, preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine. Nausea, taste change, diarrhea, and indigestion are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or do not go away. Let your doctor know about cough or throat irritation that does not go away. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. If dizziness happens, rise slowly from sitting position or avoid driving. Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function and the levels of salts such as potassium checked regularly to make sure that this medicine is working properly. Indapamide + Perindopril Erbumine is a combination of two medicines: Perindopril and indapamide which lower blood pressure effectively. Perindopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently. Indapamide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Indications

• Hypertension (high blood pressure)

Mechanism of action

Perindopril is an ACE inhibitor, which acts by inhibiting the conversion of angiotensin I to angiotensin II, reducing the activity of the sympathetic nervous system and inhibiting enzyme kininase, which is involved in the conversion of bradykinin and other substances. Indapamide is a sulfonamide derivative with an indole ring. It inhibits the reabsorption of sodium in the cortical dilution segment, thus increasing urinary output, resulting in an antihypertensive effect.

Dosage

Adult Dose: Oral Hypertension Adult: 1 tab once daily in the morning. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Avoid use. 30-60 Dose adjustment may be needed

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Indapamide + Perindopril Erbumine is to be taken empty stomach.

Side effects

Common: • Nausea • Diarrhea • Stomach pain • Constipation • Vomiting • Headache • Vertigo • Dizziness • Altered vision • Numbness • Ringing in ear • Breathlessness • Indigestion • Allergic reaction • Skin rash • Itching • Cramps • Fatigue

Precautions & warnings

[UNSAFE] Indapamide + Perindopril Erbumine may cause side effects which could affect your ability to drive. Indapamide + Perindopril Erbumine usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in some patients. This may affect your driving ability. You have been prescribed Indapamide + Perindopril Erbumine for the treatment of high blood pressure. It also lowers your risk of stroke and heart attack. Take it in the morning with breakfast, to avoid getting up at night to urinate. Indapamide + Perindopril Erbumine may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Inform you doctor about any cough, or throat irritation that doesn't go away. Indapamide + Perindopril Erbumine may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth. Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine. Do not take Indapamide + Perindopril Erbumine if you’re pregnant or planning pregnancy. It can cause birth defects or be fatal to your unborn baby.

Contraindications

Hypersensitivity. Severe renal impairment (CrCl <30 ml/min), hypokalaemia, severe hepatic impairment or hepatic encephalopathy, history of angioedema associated with treatment with an ACE inhibitor, children. Dialysis patients or patients with untreated decompensated heart failure. Hereditary/idiopathic angioneurotic oedema. Pregnancy and lactation.

Drug interactions

Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin. Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides.

Food interactions

[UNSAFE] Indapamide + Perindopril Erbumine may cause excessive drowsiness with alcohol.

Use in pregnancy

[CONSULT YOUR DOCTOR] Indapamide + Perindopril Erbumine is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Indapamide + Perindopril Erbumine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

[CAUTION] Indapamide + Perindopril Erbumine should be used with caution in patients with kidney disease. Dose adjustment of Indapamide + Perindopril Erbumine may be needed. Please consult your doctor. Caution should be advised in patients with renal impairment. [CAUTION] Indapamide + Perindopril Erbumine should be used with caution in patients with liver disease. Dose adjustment of Indapamide + Perindopril Erbumine may be needed. Please consult your doctor.

Common questions

i m 39 years old, i m a patient of hypertension, i m taking medicine Dytor plus 10, MPROL 50 mg & Coversyl AM 4/5, MY Doctor says to avoid pregnancy, is this risky for me???? Yes it maybe risky at this age and this blood pressure I am a patient of hypertension Hypertension is clinal condition of high blood pressure. Please see a physician. Some times I had lot of hypertension Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly. High blood pressure and anxiety issues. leads to twitching of hands and legs. High blood pressure requires monitoring and medicine titration plus lifestyle changes and is a life long processTake psychologist counseling and psychiatrist opinion for anxiety I have a consistent BP of 160/105. Recently went through ECG, TMT, and other blood tests including cholesterol etc. Took a health check up from Apollo Clinic. All reports are normal except BP and sugar 150/261. 3 Month sugar test report is 8. I have a family history of diabetes and BP. However never had myself. A doctor has prescribed 1/2Tab OD Amryl plus. Kindly provide opinion. Medicine prescribed is Coversyl plus instead of Amryl plus. what opinion u need, u must take all the medicine prescribed by physician High blood pressure, breathing issues Do yoga and pranayam regularly, take halleezy tablet 2 tablet twice Hypertension blood pressure pro Bp any medicine u taking I have high blood pressure. I am diabetic and am Nifedipine, metformin, aspirin, atorvastatin. I have ideal body weight. Blood pressure is 140/90 usually and my A 1C is 7.8 Total cholesterol is 200. Hdl is 50 LDL is 128 and triglycerides is 200. BUN is 20. Creatinine is 1.3 and urinalysis is unremarkable. Please advise optimal management. Medicines are ok Strict dietary precautions are advisable and go for regular walk plus meditation and yoga

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.