Cox B200mg
Rx- Generic:
- Celecoxib
- Company:
- Beximco Pharmaceuticals Ltd.
- Dosage form:
- Capsule
- Pack size:
- Capsule
৳ 8/unit
Pack: ৳ 8
At a glance
Celecoxib — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Celecoxib is a pain relieving medicine. It alleviates pain, redness, and swelling in conditions such as osteoarthritis, rheumatoid arthritis, and pain during menstruation. Celecoxib can be taken with or without food. You should take it regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and your needs. Do not take more or use it for longer than recommended by your doctor. Some common side effects of this medicine includes abdominal pain, diarrhea, indigestion, flatulence, peripheral edema, and dizziness. If any of these side effects bother you or do not go away, you should let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose. The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, and liver. You should avoid consumption of alcohol while on this medication. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctors before using this medicine as it can cause harmful effects to the developing baby. Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) called COX-2 inhibitors. It works by blocking the release of certain chemical messengers that are responsible for pain and inflammation (redness and swelling).
Indications
• Pain relief • Osteoarthritis • Rheumatoid arthritis • Pain during menstruation
Mechanism of action
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor primarily responsible to reduce mediators of pain and inflammation. Its action is due to inhibition of prostaglandin synthesis via inhibition of COX-2.
Dosage
Adult Dose: Oral Osteoarthritis Adult: 200 mg/day as a single dose or in 2 divided doses. May increase to 200 mg bid, if necessary. Rheumatoid arthritis Adult: 100-200 mg bid. Dysmenorrhoea; Pain relief Adult: Initially, 400 mg followed by 200 mg if necessary on the 1st day. Maintenance: 200 mg bid. Ankylosing spondylitis Adult: Initially, 200 mg/day as a single dose or in 2 divided doses. May increase to 400 mg/day after 6 wk. Hepatic impairment: Moderate (Child-Pugh category B): Reduce dose by 50%. Severe (Child-Pugh category C or ?10 score): Contraindicated. Child Dose: Juvenile idiopathic arthritis Child: >2 yr >10 kg to 25 kg: 100 mg bid.
Administration
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Celecoxib may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Stomach pain • Diarrhea • Flatulence • Flu-like symptoms • Peripheral edema
Precautions & warnings
[UNSAFE] Celecoxib may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Celecoxib helps relieve pain and inflammation. It may cause fewer stomach problems as compared to other NSAIDs like Ibuprofen or Naproxen. It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you. Do not consume alcohol while on treatment with this medicine as it may cause excessive drowsiness. Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment. Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function. Do not take Celecoxib if you are pregnant, planning to conceive, or breastfeeding.
Contraindications
Hypersensitivity including those in whom attacks of angioedema, rhinitis and urticaria have been precipitated by aspirin, NSAIDs or sulfonamides. Severe hepatic impairment; severe heart failure; inflammatory bowel disease; peptic ulcer; renal impairment (creatinine clearance <30 mL/min); pregnancy and lactation.
Drug interactions
May increase plasma level w/ CYP2C9 isoenzymes (e.g. fluconazole). May increase serum level of lithium. May reduce effect of antihypertensives and diuretics. May increase anticoagulant effect of warfarin.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Celecoxib.
Use in pregnancy
[CONSULT YOUR DOCTOR] Celecoxib is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Celecoxib is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[CAUTION] Celecoxib should be used with caution in patients with kidney disease. Dose adjustment of Celecoxib may be needed. Please consult your doctor. Use of Celecoxib is not recommended in patients with severe kidney disease. [CAUTION] Celecoxib should be used with caution in patients with liver disease. Dose adjustment of Celecoxib may be needed. Please consult your doctor. Use of Celecoxib is not recommended in patients with severe liver disease. Inform your doctor and stop taking this medicine if you develop any signs of liver toxicity.
Common questions
Pain.in right shoulder.RA factor negative.3yrs suffering. Take folitrax7.5mg tab and hqtor ,folvitetab ,hifennac.is it suitable or any sideeffect Where else is the pain. Just pain in shoukfer is not rheumatoid arthritis. Rheumatoid arthritis with osteoarthritis Please refer to a Rheumatologist Is Rheumatoid arthritis curable? no , but it can be controlled with YOGA and MEDICNESto give u pain free good life I have joint pain in my rt wrist since 6 yrs. What are the possible reasons? It may be Tenosynovitis, or Rheumatoid arthritis or any other type of arthritis Please suggest me medicines list to recover with rheumatoid arthritis https://www.1mg.com/otc/pain-away-tablet-otc333737One ?one tablet morning & evening after taking food , use at least 1-2 months Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason? This is the test for rheumatoid arthritis Rheumatoid arthritis pain in joints https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks Severe Joint pain in left hand wrist, elbow, shoulder and neck joint. Took some TEST and reports attached. Provided tablets are not killing the pain. Kindly help and guide us in right way. Attached Anti CCT TEST repory Looks like a case of rheumatoid arthritis.Kindly consult a rheumatologist asap