Cytocid
250mg+400mgOTC৳ 0.50/unit
Pack: ৳ 0.50
৳ 0.50/unit
Pack: ৳ 0.50
At a glance
Aluminium Hydroxide + Magnesium Hydroxide is a combination antacid used to neutralize excess stomach acid and treat heartburn, indigestion, gastritis and peptic ulcer.
Indications
Hyperacidity, peptic ulcer, gastritis, heartburn, sour stomach, dyspepsia, reflux oesophagitis.
Pharmacology
Aluminium hydroxide is a slow-acting antacid and adsorbent with prolonged effect and high neutralizing power. Magnesium hydroxide provides slow but sustained acid neutralizing properties. Aluminium hydroxide forms a protective coating over the ulcer surface to facilitate healing. Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, resulting in bowel evacuation.
Dosage
Tablet: 2 tablets 1-3 hours after meals and at bedtime, or as directed by the physician.
Suspension: 2 teaspoonfuls (10 mL) 1-3 hours after meals and at bedtime, or as directed by the physician.
Gastric Hyperacidity/Heartburn: Up to 1 g/day.
Hyperphosphataemia in Chronic Renal Failure: Up to 10 g/day in divided doses with meals.
Side effects
Common side effects:
- Aluminium hydroxide: Chalky taste, constipation, fecal impaction, stomach cramps
- Magnesium hydroxide: Diarrhea
With long-term use: Alkaluria (may predispose to nephrolithiasis by forming calcium phosphate precipitation)
Serious (rare): Aluminium intoxication (in chronic renal failure), hypophosphataemia, osteomalacia, hypermagnesaemia, alkalosis.
Use in pregnancy
It is advised to avoid antacid preparations in the first trimester of pregnancy.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in chronic renal impairment (risk of aluminium accumulation)
- Caution in congestive heart failure, oedema, cirrhosis, and low sodium diets
- Caution in patients with recent gastrointestinal haemorrhage
- Maintain 2 hour gap with other medications (to avoid absorption interference)
- Avoid use in the first trimester of pregnancy
- Caution during lactation
Overdose effects
Overdose symptoms: severe constipation, intestinal obstruction, diarrhea, electrolyte imbalance. Treatment: drug discontinuation and symptomatic measures.
Storage conditions
Store below 30°C, protected from light and moisture. Keep out of reach of children.