৳ 45/unit
Pack: ৳ 450
৳ 45/unit
Pack: ৳ 450
At a glance
Empagliflozin + Linagliptin is a combination medicine used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Indications
Type 2 diabetes mellitus
Pharmacology
Empagliflozin is an SGLT2 inhibitor that reduces renal glucose reabsorption. Linagliptin is a DPP-4 inhibitor that increases GLP-1 and GIP levels.
Dosage
10 mg empagliflozin + 5 mg linagliptin once daily in the morning. May be increased to 25 mg/5 mg. eGFR less than 45 mL/min/1.73 m2: Do not initiate.
Side effects
Pancreatitis ketoacidosis volume depletion urinary tract infections hypoglycemia Fournier's gangrene genital mycotic infections hypersensitivity reactions severe arthralgia bullous pemphigoid heart failure.
Use in pregnancy
Not recommended during the second and third trimesters of pregnancy.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Pancreatitis has been reported with linagliptin. Ketoacidosis has been reported with SGLT2 inhibitors. Empagliflozin can cause volume depletion. SGLT2 inhibitors increase UTI risk.
Overdose effects
In the event of an overdose employ usual supportive measures.
Storage conditions
Store below 30 degrees Celsius away from light and wet place.