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At a glance

Epinastine Hydrochloride 0.05% Eye prep is an antihistamine medication used to treat allergic eye inflammation, redness, and itching.

Indications
  • Allergic eye disease: Indicated for the treatment of signs and symptoms of allergic conditions of the anterior segment of the eye.
Pharmacology

Epinastine is a topically active antihistamine that antagonizes both histamine H1 and H2 receptors. Moreover, it has mast cell stabilizing activity and prevents the release of inflammatory mediators from the blood vessel. Epinastine does not penetrate the blood-brain barrier and therefore is not expected to induce side effects on the central nervous system.

Dosage

Adult Dose:

  • Allergic conjunctivitis: Instill 1 drop in affected eye twice daily.

Child Dose (>2 years):

  • Allergic conjunctivitis: Instill 1 drop in affected eye twice daily.
Side effects

Common Side Effects:

  • Ocular hyperemia
  • Itching
  • Burning sensation in eye
  • Mild burning sensation
  • Folliculosis
  • Pruritus
  • Cold symptoms and upper respiratory infections
Use in pregnancy

Use in Pregnancy: Epinastine Hydrochloride may be unsafe to use during pregnancy. Animal studies have shown harmful effects on the developing baby. Should be used only if the potential benefit justifies the potential risk to the fetus.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Precautions:

  • Epinastine Hydrochloride 0.05% Eye prep may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
  • Your doctor has prescribed this to treat inflammation due to allergies of the eye.
  • Apply pressure on the corner of the eye (close to the nose) for about 1 minute immediately after instilling the drop.
  • Wait for at least 5-10 minutes before delivering the next medication in the same eye.
  • Make sure to use within 4 weeks of opening the bottle.
  • For ophthalmic use only. Patients should be advised not to wear contact lenses if their eye is red.
Overdose effects

Overdose: Limited information is available on overdose. Excessive use may cause eye irritation.

Storage conditions

Storage: Store in a cool & dry place, protect from light. Do not use longer than one month after the first opening. Keep out of reach of children.

Epinastine Hydrochloride 0.05% Eye prep — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.