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At a glance

Pseudoephedrine + Triprolidine is a combination medicine used for relief of common cold symptoms such as runny nose, stuffy nose, sneezing, watery eyes, and congestion. Pseudoephedrine is a decongestant that narrows small blood vessels to relieve nasal congestion, and Triprolidine is an antiallergic that relieves allergy symptoms.

Indications
  • Common cold symptoms (runny nose, stuffy nose, sneezing, watery eyes, congestion)
Pharmacology

Pseudoephedrine stimulates alpha-adrenergic receptors of the respiratory mucosa, causing vasoconstriction and reducing nasal mucosal swelling and congestion. Triprolidine blocks H1 receptors, preventing histamine effects and relieving allergy symptoms (runny nose, sneezing, watery eyes).

Dosage

Adult Dose (Oral):

  • Allergic rhinitis/Cold and flu: 1 tablet every 4-6 hours, up to 4 times daily

Pediatric Dose (Oral):

  • >12 years: Same as adult
Side effects

Common Side Effects:

  • Nausea
  • Stomach discomfort
  • Headache
  • Nervousness
  • Restlessness
  • Insomnia
  • Dizziness
  • Drowsiness
Use in pregnancy

Use in Pregnancy: May be unsafe during pregnancy; animal studies have shown harmful effects; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • May affect driving ability; do not drive if drowsy or dizzy
  • Avoid alcohol (excessive drowsiness)
  • Do not use in severe hypertension, coronary artery disease, or with or within 2 weeks of MAOIs
  • Caution in kidney or liver disease
Overdose effects

No overdose information available; consult your doctor if taken in excess.

Storage conditions

Store in a cool and dry place; keep out of reach of children.

Pseudoephedrine + Triprolidine — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.