৳ 160/unit
Pack: ৳ 160
৳ 160/unit
Pack: ৳ 160
At a glance
Adapalene 0.1% + Benzoyl Peroxide 2.5% is a topical gel used for the treatment of acne vulgaris in patients 12 years of age and older. Adapalene normalizes skin cell differentiation and Benzoyl Peroxide kills acne-causing bacteria.
Indications
Acne vulgaris, in patients 12 years of age and older.
Pharmacology
Adapalene binds to specific retinoic acid nuclear receptors but does not bind to cytosolic receptor protein. Biochemical and pharmacological profile studies have demonstrated that Adapalene is a modulator of cellular differentiation, keratinization and inflammatory processes. Adapalene binds with specific retinoic acid nuclear receptors that normalize the differentiation of follicular epithelial cells resulting in decreased microcomedone formation. Benzoyl peroxide is an oxidizing agent with bacteriocidal and keratolytic effects.
Dosage
Patients 12 years and older:
- Apply a thin film of gel to affected areas of the face and/or trunk once daily at bedtime
- Use a pea-sized amount for each area of the face (e.g., forehead, chin, each cheek)
- Avoid eyes, lips and mucous membranes
Side effects
Common side effects:
- Erythema (skin redness)
- Scaling (skin peeling)
- Dry skin
- Stinging/burning at application site
- Skin irritation
- Contact dermatitis
- Application site burning
Use in pregnancy
Pregnancy Category: C. No adequate controlled studies in pregnant women. Use only if potential benefit justifies risk to the fetus.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Avoid exposure to sunlight and sunlamps (skin becomes more sensitive)
- Use sunscreen and protective apparel (e.g., hat) when sun exposure cannot be avoided
- Do not apply to broken, sunburnt or sensitive areas of skin
- May bleach hair, clothing, and furnishings (be careful when applying to large areas)
- Rinse with water immediately if contact with eyes or mouth occurs
- Consult your doctor if pregnant, planning pregnancy or breastfeeding
Overdose effects
Topical overdose is unlikely; excessive application may cause skin irritation.
Storage conditions
Store below 25°C in a cool and dry place, protected from light and moisture. Keep out of reach of children. Keep the tube tightly closed after use.