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At a glance

Lidocaine (Lignocaine) Hydrochloride is a local anesthetic used to temporarily numb certain areas of the body. It is used as an anesthetic lubricant for insertion of instruments in medical procedures and for treatment of painful inflammation of the urethra and bladder.

Indications
  • Local anesthesia (numb tissues in a specific area)
  • Treatment of painful inflammation of the urethra and bladder
  • Anesthetic lubricant for medical procedures (e.g., catheters)
Pharmacology

Lidocaine stabilizes the neuronal membrane and inhibits Na+ ion movements to block pain signals from nerves to the brain.

Dosage

Adult Dose (IV - Ventricular Arrhythmias):

  • Bolus: 1-1.5 mg/kg slow IV over 2-3 minutes
  • Repeat: 0.5-0.75 mg/kg in 5-10 minutes, up to 3 mg/kg total
  • Continuous infusion: 1-4 mg/min IV

Regional Anesthesia (IV): 4 mg/kg

Epidural: Lumbar: 250-300 mg; Thoracic: 200-300 mg; Caudal (Obstetric): 200-300 mg

Side effects

Common Side Effects:

  • Allergic reaction
  • Application site reactions (burning, irritation, itching, and redness)
Use in pregnancy

Use in Pregnancy: Lidocaine (Lignocaine) Hydrochloride is generally considered safe during pregnancy. Animal studies have shown low or no adverse effects to the developing baby.

Precautions & warnings
  • Do not apply to broken or infected skin
  • Avoid contact with eyes, mouth, and nose
  • Do not cover with airtight dressings (risk of side effects)
  • Consult doctor if no improvement in 2-4 weeks
  • Inform doctor if you have liver disease or heart rhythm problems
Overdose effects

No specific overdose information available; symptomatic and supportive measures should be employed.

Storage conditions

Store below 30°C in a dry place, away from light; keep out of reach of children.

Lidocaine (Lignocaine) Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.