৳ 111.10/unit
Pack: ৳ 111.10
৳ 111.10/unit
Pack: ৳ 111.10
At a glance
Gentamicin 0.3% + Hydrocortisone Acetate 1% Eye prep is a combination medicine used for bacterial eye infections and inflammation.
Indications
- Susceptible infections
- Keratitis
- Allergic conjunctivitis
- Blepharitis
- Allergic and inflammatory conditions of the eye
- Chronic conjunctivitis
- Spring catarrh
Pharmacology
Gentamicin is an aminoglycoside that binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective. Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability.
Dosage
Adult Dose (Ophthalmic):
- Eye drops: Instill 1-2 drops 4 hourly, up to 2 drops hourly in severe cases
- Eye ointment: Apply 1/2 inch into the conjunctival sac 2-3 times daily
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Allergic contact dermatitis
- Transient irritation
- Burning
- Stinging
- Increased redness
- Lacrimation
Use in pregnancy
Use in Pregnancy: Unsafe during pregnancy. Animal studies have shown harmful effects.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Caution with concurrent use of neuromuscular blocking agents.
- Caution in myasthenia gravis, parkinsonism.
- Caution in conditions predisposing to ototoxicity and nephrotoxicity.
- Monitor plasma concentrations in high doses or prolonged courses.
Overdose effects
Overdose: Overdose is unlikely when used as directed. Excessive use may cause eye irritation.
Storage conditions
Storage: Store in a cool and dry place. Protect from light and freezing. Discard contents one month after opening.