৳ 55/unit
Pack: ৳ 55
৳ 55/unit
Pack: ৳ 55
At a glance
Esomeprazole + Amoxicillin + Clarithromycin Kit is a combination medicine used for the treatment of peptic ulcer disease caused by H. pylori bacteria. It contains two antibiotics and an antacid that eradicates the infection and relieves acid-related symptoms.
Indications
Peptic ulcer disease (active chronic gastric, duodenal and gastric ulcers caused by H. pylori infection).
Pharmacology
Esomeprazole irreversibly inhibits H+/K+ ATPase enzyme in gastric parietal cells to suppress gastric acid secretion. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Clarithromycin inhibits protein synthesis by binding to the 50S ribosomal subunit.
Dosage
Twice daily (morning and evening) for 7-14 days. Each strip contains 1 Esomeprazole 20mg capsule, 2 Amoxicillin 500mg tablets and 1 Clarithromycin 500mg tablet.
Side effects
Common side effects: Diarrhea, nausea, vomiting, stomach pain, taste change, flatulence, headache, rash. Serious side effects: Allergic reactions (rash, itching, swelling of face, breathing difficulty).
Use in pregnancy
Use during pregnancy only if clearly needed. Animal studies have shown harmful effects on the fetus.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Unsafe during pregnancy. Caution during lactation. Dose adjustment may be needed in kidney disease. Safe in liver disease. Avoid alcohol. Caution while driving.
Overdose effects
Limited information on overdose. May cause diarrhea, nausea and stomach pain.
Storage conditions
Store below 30°C in a cool and dry place. Keep out of reach of children.