Lapen 12 Lac

• Group-A beta-haemolytic streptococcal infections
• Syphilis
• Prevention of rheumatic fever
• Acute otitis media

Benzathine benzylpenicillin has the same antimicrobial action as benzylpenicillin which exerts its bactericidal action on growing and dividing bacteria by inhibiting bacterial cell wall synthesis. IM administration results in a prolonged effect, but because of its relatively low blood concentrations, its use should be restricted to microorganisms that are highly susceptible to it.

Adult Dosage:

• Group-A beta-haemolytic streptococcal infections: 600,000 units as a single IM dose
• Prevention of rheumatic fever: 1.2 million units monthly IM injection
• Acute otitis media: 600,000 units as a single injection
• Early syphilis: 2.4 million units as a single dose
• Late syphilis: 2.4 million units weekly for 3 successive weeks
• Neurosyphilis: IV benzylpenicillin 2-4 million units every 4 hours for 10 days, followed by benzathine penicillin 2.4 million units weekly for 3 weeks

Pediatric Dosage:

• Newborns and infants: 50,000 units/kg as a single dose
• Children >60 lb: 900,000 units as a single dose

• Injection site pain, swelling, redness
• Rash
• Allergic reactions
• Nausea
• Diarrhea

[SAFE IF PRESCRIBED] Benzathine Penicillin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby.

• Inform your doctor if allergic to penicillin or cephalosporin antibiotics
• Complete the full course - do not stop even if you feel better
• Stop and inform your doctor immediately if you develop allergic reactions (rash, swelling of face/throat/tongue, breathing difficulties)
• Ischaemic reactions may occur at injection site

Overdose may cause nausea, vomiting, diarrhea, and electrolyte imbalance. Consult a doctor if symptoms occur.

Store below 30°C, away from light and moisture.