Lefabac 600
Rx- Generic:
- Lefamulin
- Company:
- ACI Limited
- Dosage form:
- Tablet
- Pack size:
- Box (10 Tablet)
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৳ 850/unit
Pack: ৳ 8,500
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At a glance
Lefamulin is an antibiotic used for the treatment of community-acquired bacterial pneumonia (CABP). It is a first-in-class semi-synthetic pleuromutilin antibiotic that works by inhibiting bacterial protein synthesis.
Indications
- Community-acquired bacterial pneumonia (CABP) - caused by susceptible microorganisms: Streptococcus pneumoniae, Staphylococcus aureus (methicillin-susceptible), Haemophilus influenzae, Legionella pneumophila, Mycoplasma pneumoniae, Chlamydophila pneumoniae
Dosage
Adult Dose:
- Injection (IV): 150 mg every 12 hours, 60-minute IV infusion, 5-7 days
- Tablet (PO): 600 mg every 12 hours, 5 days
- Dose adjustment required for severe hepatic impairment (IV: 150 mg every 24 hours; Tablets: not recommended)
Side effects
Common Side Effects:
- Diarrhea
- Nausea
- Injection site reactions
- Elevated liver enzymes
- Vomiting
- Potential for QT interval prolongation
Precautions & warnings
- Potential for QT interval prolongation - avoid in patients with prolonged QT, ventricular arrhythmias, or taking QT-prolonging drugs
- Clostridioides difficile-associated diarrhea (CDAD) - reported with nearly all systemic antibacterial agents
- Dose adjustment needed for severe hepatic impairment
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.