Liquical0.25mcg
Rx- Generic:
- Calcitriol
- Company:
- Beacon Pharmaceuticals PLC
- Dosage form:
- Capsule
- Pack size:
- Capsule
৳ 10.06/unit
Pack: ৳ 10.06
Price comparison
- This brand
- ৳ 10.06
- Cheapest of this genericColitrol
- ৳ 10
The cheaper brand costs ৳ 0.06 less per unit
Compared against 8 brands
At a glance
Calcitriol is the active form of Vitamin D that increases Vitamin D and calcium levels in the blood. It is used in the treatment of postmenopausal osteoporosis, renal osteodystrophy, hypoparathyroidism, and vitamin D-dependent rickets.
Indications
- Post-menopausal osteoporosis
- Renal osteodystrophy
- Postsurgical hypoparathyroidism
- Idiopathic hypoparathyroidism
- Pseudohypoparathyroidism
- Secondary hyperparathyroidism in chronic renal failure
- Vitamin D dependent rickets
Dosage
Postmenopausal Osteoporosis: 0.25 mcg twice daily OR 0.50 mcg once daily.
Renal Osteodystrophy (Dialysis patients): Initial 0.25 mcg/day; normal or slightly reduced calcium: 0.25 mcg every other day; hemodialysis patients: 0.5-1 mcg/day.
Hypoparathyroidism & Rickets: Initial 0.25 mcg/day (morning); increase every 2-4 weeks if needed.
Secondary Hyperparathyroidism (Pre-dialysis): 0.25 mcg/day; may increase to 0.5 mcg/day if needed.
Hypocalcemia in Premature Infants: 1 mcg/day (oral) for 5 days.
Injection (IV): 1-2 mcg three times weekly (approximately every other day); doses of 0.5-4 mcg have been used. Increase by 0.5-1 mcg every 2-4 weeks if needed.
Serum creatinine monitoring: At 4 weeks, 3 and 6 months, and every 6 months thereafter.
Side effects
Early side effects: Weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain, metallic taste.
Late side effects: Polyuria, polydipsia, anorexia, weight loss, nocturia, conjunctivitis (calcific), pancreatitis, photophobia, rhinorrhea, pruritus, hyperthermia, decreased libido, elevated BUN, albuminuria, hypercholesterolemia, elevated SGOT/SGPT, ectopic calcification, hypertension, cardiac arrhythmias, rarely psychosis.
Mild pain on injection may occur.
Precautions & warnings
- Excessive dosage may cause hypercalcemia; caution in patients on digitalis (hypercalcemia may precipitate cardiac arrhythmias).
- Withhold vitamin D and its derivatives during treatment.
- Use non-aluminum phosphate-binding compounds to control serum phosphorus in dialysis patients.
- Chronic hypercalcemia may lead to vascular calcification, nephrocalcinosis, and soft-tissue calcification.
- If hypercalcemia develops, discontinue immediately.
- Avoid antacids (magnesium-containing antacids may cause hypermagnesemia).
- Drink plenty of fluids (avoid dehydration).