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Company•Nevian Lifescience PLC

Lucentis

10mg/mlRx
Generic: Ranibizumab

৳ 100,000/unit

Pack: ৳ 100,000

Injection0.3ml (3.0mg) vial
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At a glance

Ranibizumab is a humanized monoclonal antibody against VEGF-A used for neovascular (wet) age-related macular degeneration (AMD), macular edema following retinal vein occlusion (RVO), diabetic macular edema (DME), diabetic retinopathy, and myopic choroidal neovascularization (mCNV).

Indications
  • Neovascular (wet) age-related macular degeneration (AMD)
  • Macular edema following retinal vein occlusion (RVO)
  • Diabetic macular edema (DME)
  • Diabetic retinopathy (NPDR, PDR) in patients with DME
  • Myopic choroidal neovascularization (mCNV)
Pharmacology

Ranibizumab binds to the receptor binding site of VEGF-A, preventing interaction with VEGFR1 and VEGFR2 on endothelial cell surfaces. It reduces endothelial cell proliferation, vascular leakage, and new blood vessel formation, helping prevent vision loss in neovascular AMD, DME, and RVO.

Dosage

Adult Dose (Intravitreal):

  • Neovascular AMD: 0.5 mg (0.05 mL of 10 mg/mL solution) once monthly
  • Macular edema in RVO: 0.5 mg once monthly for 6 months
  • DME and DR: 0.3 mg (0.05 mL of 6 mg/mL solution) once monthly
  • mCNV: 0.5 mg once monthly for up to 3 months; may retreat if needed
Side effects

Side Effects:

  • Conjunctival hemorrhage
  • Eye pain
  • Eye inflammation
  • Increased intraocular pressure
  • Endophthalmitis
  • Retinal detachment
  • Thromboembolic events
Use in pregnancy

Use in Pregnancy: May be unsafe during pregnancy; animal studies have shown harmful effects; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • May cause temporary visual disturbances after injection; do not drive until vision is clear
  • Monitor intraocular pressure before and after injection
  • Use aseptic technique to prevent infection
  • Do not use in active or suspected ocular/periocular infection or active severe intraocular inflammation
Overdose effects

No overdose information available; consult your doctor if overused.

Storage conditions

Store at 2-8°C; protect from light; keep out of reach of children.

Ranibizumab — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.