Methigic 4
Rx- Generic:
- Methylprednisolone
- Company:
- Square Pharmaceuticals PLC.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
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৳ 5/unit
Pack: ৳ 50
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At a glance
Methylprednisolone is a potent corticosteroid used to treat inflammation, allergies, rheumatic disorders, skin and eye diseases, and nephrotic syndrome.
Indications
- Rheumatic Disorders (Rheumatoid Arthritis, Ankylosing Spondylitis, Gouty Arthritis)
- Collagen Diseases (Systemic Lupus Erythematosus, Dermatomyositis)
- Dermatologic Diseases (Pemphigus, Exfoliative Dermatitis, Psoriasis)
- Allergies (Bronchial Asthma, Contact Dermatitis)
- Ophthalmic Diseases (Iritis, Keratitis, Allergic Conjunctivitis)
- Respiratory Diseases (Sarcoidosis, Aspiration Pneumonitis)
- Hematologic Disorders (Idiopathic Thrombocytopenic Purpura, Hemolytic Anemia)
- Neoplastic Diseases (Leukemias, Lymphomas)
- Edematous States (Nephrotic Syndrome)
- CNS Diseases (Multiple Sclerosis)
- Endocrine Disorders (Adrenocortical Insufficiency)
Dosage
Adult Dose (Oral):
- Anti-inflammatory/Immunosuppressive: Initial: 4-48 mg daily (1-4 divided doses as needed)
- Allergic Conditions: 24 mg (Day 1), 20 mg (Day 2), 16 mg (Day 3), 12 mg (Day 4), 8 mg (Day 5), 4 mg (Day 6)
- Maintenance: Lowest effective dose based on patient response
- Multiple Sclerosis: 160 mg daily for 1 week, then 64 mg every other day for 1 month
Child Dose: 0.5-1.7 mg/kg daily or 5-25 mg/m² daily (6-12 hourly intervals)
Alternate-day therapy (ADT): Twice the daily dose every other morning (to minimize side effects in long-term use)
Side effects
Common Side Effects:
- Skin thinning
- Increased risk of infection
- Reduction in bone density
- Weight gain
- Mood changes
- Upset stomach
- Behavioral changes
Long-term/High-dose:
- Fluid retention, weight gain, hypertension
- Potassium loss, headache
- Muscle weakness, osteoporosis
- Glaucoma, cataracts
- Peptic ulcer, growth retardation (children)
- Convulsions, psychiatric disorders (depression, euphoria, insomnia)
Precautions & warnings
- Do not stop abruptly (risk of adrenal insufficiency)
- Inform doctor if signs of infection (fever, sore throat) occur
- Do not receive live vaccines
- Monitor blood glucose if diabetic
- Caution in osteoporosis, mood disorders, hypertension, liver disease
- Enhanced effect in hypothyroidism and cirrhosis
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.