Mirader 25

Mirabegron is used to treat symptoms of overactive bladder that includes increased or frequent urination, urgent need to urinate and inability to control urination. It helps to relax the muscle surrounding the bladder and increase it's ability to store urine. Mirabegron is advised to take it in a dose and duration as per prescription. It can be taken with or without food. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine. Some common side effects of this medicine are hypertension, common cold symptoms (nasopharyngitis), urinary tract infection, and headache. If any of the side effects bother you or persist, consult the doctor without delay. Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you are pregnant or breastfeeding, tell your doctor prior to the treatment. Patients with liver or kidney disease must be cautious while receiving the prescription and they must receive regular follow-ups as per the doctor's advice. Mirabegron is a beta 3-receptor agonist. It works by activating the receptor in the bladder, causing the bladder muscles to relax. It prevents frequent, urgent or uncontrolled urination.

• Overactive bladder (OAB) symptoms

Beta-3 adrenergic receptor agonist which causes relaxation of the detrusor smooth muscle of the urinary bladder and increases bladder capacity.

Adult Dose: Overactive Bladder Indicated for overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency 25 mg PO qDay 25 mg dose is typically effective within 8 weeks May increase to 50 mg PO qDay based on individual efficacy and tolerability Hepatic impairment Moderate (Child-Pugh B): Not to exceed 25 mg/day Severe (Child Pugh C): Not recommended Renal Dose: Renal impairment Severe (CrCl 15-29 mL/min): Not to exceed 25 mg/day ESRD: Not recommended

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mirabegron may be taken with or without food, but it is better to take it at a fixed time.

Common: • Constipation • Headache • High blood pressure • Nasal inflammation • Urinary tract infection

[SAFE] Mirabegron does not usually affect your ability to drive. Mirago 50 Tablet ER helps you to have better control over your urination. It relaxes your bladder which increases its capacity to hold urine thereby reducing the need to pass urine. It causes less drowsiness and constipation than other medicines for overactive bladder. It may raise your blood pressure. Monitor your blood pressure regularly. Do not stop taking this medicine if you do not notice an improvement in your symptoms as it may take some time for your bladder to adapt and your symptoms to improve.

Hypersensitivity. Severe uncontrolled HTN.

Increased AUC of strong CYP3A/P-gp inhibitors eg, ketoconazole, itraconazole, ritonavir, clarithromycin. Decreased plasma conc by CYP3A/P-gp inducers. Increased Cmax & AUC of metoprolol, despiramine & digoxin. Thioridazine, type 1C antiarrhythmics (eg flecainide, propafenone), TCAs. Potential P-gp inhibition of dabigatran.

[CAUTION] Caution is advised when consuming alcohol with Mirabegron. Please consult your doctor.

[CONSULT YOUR DOCTOR] Mirabegron may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Mirabegron is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CAUTION] Mirabegron should be used with caution in patients with severe kidney disease. Dose adjustment of Mirabegron may be needed. Please consult your doctor. [CAUTION] Mirabegron should be used with caution in patients with liver disease. Dose adjustment of Mirabegron may be needed. Please consult your doctor. Use of Mirabegron is not recommended in patients with severe liver disease.

I feel some time to urine again after urine but no pain fever burning sensation last time I show to one doctor can u check the report is any abnormal This microsopic report is normal U may be having overactive bladder get urodynamics bladder pressure study Sir my daughter PATIENT a uti patient.puss cells are 10-15 .urine culture is normal. Usg shows overactive bladder she is taking dariff And contiflo.how much time will it take for her treatment with this medicine. y is she taking contiflo icon for overactive bladder Urine leakage, overactive bladder Hi kindly share details history & reports Overactive bladder having frequent urination. Cannot control urge of urine. https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks Overactive urinary bladder is my problem. But I'd like to change the medication because of side effects from the present drug I'm using. Take mahayograj guggul 2 tab twice, chandraprabha vati 2 tablet twice with water. Do Yoga and pranayam Getting a overactive bladder thing Continuous urination problem really pissing me off Can't able to control that feeling Get urine routine examination n culture done Amar pata gas er problem Please elaborate your symptoms, history, treatment and investigations done. Uncontrollably urine and bed wetting I had spina bifida when I born, so I have a problem in controlling urine and the main problem is bed wetting while sleeping There is nothing much u can do get urine routine examination n culture ultrasound kub with PVR u r having overactive bladder probably u can start anti cholinergics after consulting ur local if ur reports are normal