৳ 1/unit
Pack: ৳ 1
৳ 1/unit
Pack: ৳ 1
At a glance
Mitomycin is an antineoplastic antibiotic used for the treatment of pancreatic breast lung and stomach cancers.
Indications
- Pancreatic cancer
- Breast cancer
- Non-small cell lung cancer
- Stomach cancer
- Superficial bladder tumors
Pharmacology
Mitomycin is enzymatically reduced to an active metabolite within susceptible cells which causes DNA cross-linking.
Dosage
Adult Dose:
- Solid Tumors (IV): 4-10 mg (0.06-0.15 mg/kg) every 1-6 weeks
- Combination Therapy: 10 mg/m²
- Intravesical (Bladder Tumor): 20-40 mg weekly or 3 times weekly
Child Dose: Safety and efficacy not established.
Side effects
Common Side Effects:
- Anemia (low red blood cells)
- Decreased white blood cell count
- Increased bleeding tendency
- Loss of appetite
- Nausea and vomiting
- Weight loss
- Skin rash
Serious Side Effects:
- Hemolytic uremic syndrome
- Pulmonary toxicity
- Cardiotoxicity
Use in pregnancy
Use in Pregnancy: Highly unsafe. Contraindicated during pregnancy.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution while driving
- Caution in renal disease heart disease respiratory disorders
- Increased risk of infection and bleeding
- Contraindicated in pregnancy and lactation
Overdose effects
Overdose may cause bone marrow suppression severe infection and bleeding. Supportive treatment.
Storage conditions
Store in a cool and dry place protected from light.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.