৳ 14/unit
Pack: ৳ 140
৳ 14/unit
Pack: ৳ 140
At a glance
Naftopidil is a selective α1-adrenergic receptor antagonist used for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). It relaxes smooth muscle in urethra and prostate to ease urination.
Indications
- Benign prostatic obstruction
- Lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)
Pharmacology
Naftopidil is a selective α1-adrenergic receptor antagonist with higher antagonistic effect on α1D receptor. It relieves smooth muscle tension in urethra and prostate gland and suppresses detrusor muscle overactivity, making urination easier.
Dosage
Adult Dose (Oral):
- Initial: 25 mg once daily (after meal)
- If insufficient: Gradually increase to 50-75 mg once daily at 1-2 week intervals
- Maximum daily dose: 75 mg
Side effects
Common Side Effects:
- Dizziness
- Headache
- Fatigue
- Blurred vision
- Stomach discomfort
Use in pregnancy
Use in Pregnancy: No controlled studies in pregnant women; use only if clearly needed.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in patients with salt imbalance, orthostatic hypotension and diabetes
- Risk of temporary loss of consciousness due to sudden blood pressure decrease
- Caution while driving (may cause dizziness)
Overdose effects
Overdose: Symptomatic and supportive measures should be instituted.
Storage conditions
Store below 30°C in a dry place, protected from light; keep out of reach of children.