৳ 1/unit
Pack: ৳ 1
৳ 1/unit
Pack: ৳ 1
At a glance
Naltrexone is an opioid antagonist used for opioid dependence and alcohol addiction. It blocks the euphoric effects of opioids and alcohol to reduce craving.
Indications
- Opioid dependence (prevention of relapse after detoxification)
- Alcohol addiction
Pharmacology
Naltrexone acts as a competitive antagonist at opioid receptor sites. It blocks the action of opioids and precipitates withdrawal symptoms in opioid-dependent individuals.
Dosage
Opioid Dependence:
- Oral: 25 mg initially, observe for 1 hr, then 50 mg once daily (from day 2)
- IM: 380 mg every 4 weeks (maintenance)
Alcohol Addiction:
- Oral: 50 mg once daily for <12 weeks
- IM: 380 mg every 4 weeks (maintenance)
Side effects
Common Side Effects:
- Joint pain
- Fainting
- Decreased libido
- Muscle pain
- Insomnia
- Increased thirst
- Decreased sexual function
- Fatigue, nausea, abdominal pain, diarrhea
Use in pregnancy
Use in Pregnancy: Naltrexone may be unsafe during pregnancy; animal studies show evidence of fetal harm.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Patient must be opioid-free for 7-10 days before use
- Naloxone challenge test must be negative
- Monitor liver function regularly
- Caution while driving (may cause fatigue or dizziness)
Overdose effects
Overdose may cause opioid withdrawal symptoms; symptomatic treatment.
Storage conditions
Store in a dry place, away from light; keep out of reach of children.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.