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At a glance

Dexamethasone + Neomycin + Polymyxin B is an eye preparation used for the treatment of ocular inflammation with suspected or confirmed bacterial infection.

Indications
  • Bacterial eye infections
  • Ocular inflammation with suspected or confirmed bacterial infection
Pharmacology

Dexamethasone is a corticosteroid with mainly glucocorticoid activity used for its anti-inflammatory action. Neomycin is a broad-spectrum aminoglycoside antibiotic. Polymyxin B is active only against gram-negative bacteria especially Pseudomonas aeruginosa.

Dosage

Adult: Instill 1-2 drops into the conjunctival sac(s) of the affected eye(s) up to 4-6 times daily (may be used up to hourly in severe disease). Reduce frequency once condition improves.

Side effects

Common: Blurred vision, cataract, raised intraocular pressure, stinging, conjunctival hemorrhage, glaucoma, vitreous detachment, hives, rash, itching, eye pain.

Use in pregnancy

Pregnancy Category C. Corticosteroids may be teratogenic. Should be used during pregnancy only if potential benefit justifies potential risk. Prolonged or repeated use may increase risk of intra-uterine growth retardation.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Prolonged use may cause glaucoma, optic nerve damage, posterior subcapsular cataract formation, and increased risk of secondary ocular infections. Increased risk of perforations in diseases causing thinning of the cornea or sclera. Corticosteroids may mask or worsen infections. Regular IOP monitoring recommended if used for ≥10 days.

Overdose effects

No adequate information on overdose is available.

Storage conditions

Store in a cool and dry place.

Dexamethasone + Neomycin + Polymyxin B (Eye Prep) — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.