৳ 5/unit
Pack: ৳ 50
৳ 5/unit
Pack: ৳ 50
At a glance
Nimodipine is a calcium channel blocker used to prevent neurological damage after subarachnoid hemorrhage (bleeding around the brain). It dilates narrowed blood vessels in the brain to improve blood flow.
Indications
- Prophylaxis of neurological deficit following subarachnoid haemorrhage
Pharmacology
Nimodipine blocks calcium channels to relax vascular smooth muscle and prevent cerebral vasospasm. Its high lipophilicity makes it more effective on cerebral vessels.
Dosage
Adult Dose (Oral):
- 60 mg every 4 hours beginning within 4 days of hemorrhage, continued for 21 consecutive days
Hepatic Impairment: 30 mg every 4 hours
Side effects
Common Side Effects:
- Headache
- Dizziness
- Flushing
- Heartburn
- Fast or slow heartbeat
- Upset stomach, stomach pain
- Constipation
- Depression
- Decreased blood pressure
- Edema
Use in pregnancy
Use in Pregnancy: Nimodipine may be unsafe during pregnancy; animal studies show evidence of birth defects.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not abruptly discontinue
- Monitor blood pressure regularly
- Dose reduction needed in liver disease
- Caution while driving (may cause dizziness)
- Avoid alcohol
Overdose effects
Overdose: Peripheral vasodilation, decreased blood pressure and reflex tachycardia; supportive treatment.
Storage conditions
Store below 30°C; protect from light & moisture; keep out of reach of children.