oshudhkosh

Norzim12.5mg+5mg

Rx
Dosage form:
Tablet
Pack size:
Strip (10 Tablet)

৳ 10/unit

Pack: ৳ 100

At a glance

Amitriptyline + Chlordiazepoxide — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Amitriptyline + Chlordiazepoxide is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety. Amitriptyline + Chlordiazepoxide is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions. Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts. Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Amitriptyline + Chlordiazepoxide is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Indications

• Depression

Mechanism of action

Amitriptyline + Chlordiazepoxide is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitriptyline + Chlordiazepoxide may be taken with or without food, but it is better to take it at a fixed time.

Side effects

Common: • Constipation • Difficulty in urination • Weight gain • Confusion • Orthostatic hypotension (sudden lowering of blood pressure on standing) • Tiredness • Blurred vision • Dryness in mouth • Increased heart rate • Uncoordinated body movements • Depression • Memory impairment

Precautions & warnings

[UNSAFE] Amitriptyline + Chlordiazepoxide may cause side effects which could affect your ability to drive. As Amitriptyline + Chlordiazepoxide may make you feel drowsy or affect your concentration and this may affect your ability to drive.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Amitriptyline + Chlordiazepoxide.

Use in pregnancy

[CONSULT YOUR DOCTOR] Amitriptyline + Chlordiazepoxide is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Use in lactation

[CONSULT YOUR DOCTOR] Amitriptyline + Chlordiazepoxide is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Renal / hepatic impairment

[SAFE IF PRESCRIBED] Amitriptyline + Chlordiazepoxide is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amitriptyline + Chlordiazepoxide may not be needed in these patients. Please consult your doctor. [CAUTION] Amitriptyline + Chlordiazepoxide should be used with caution in patients with liver disease. Dose adjustment of Amitriptyline + Chlordiazepoxide may be needed. Please consult your doctor.

Common questions

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⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.