Olmesafe-HT 20/12.5
20mg+12.5mgRx৳ 8/unit
Pack: ৳ 80
৳ 8/unit
Pack: ৳ 80
At a glance
Olmesartan Medoxomil + Hydrochlorothiazide is a combination used for hypertension. Olmesartan blocks AT1 receptors to dilate blood vessels and hydrochlorothiazide acts as a diuretic to remove excess water and electrolytes, lowering blood pressure.
Indications
- Hypertension (high blood pressure)
Pharmacology
Olmesartan blocks AT1 receptors to dilate blood vessels. Hydrochlorothiazide inhibits sodium and chloride reabsorption in renal tubules to produce diuretic effect, reducing plasma volume and blood pressure.
Dosage
Adult Dose (Oral):
- Initial: 20/12.5 mg (olmesartan/HCTZ) once daily
- Titrate at 2-4 week intervals to 40/25 mg based on blood pressure response
Side effects
Common Side Effects:
- Nausea
- Headache
- Dizziness
- Hyperuricemia
- Upper respiratory tract infection
- Urinary tract infection
- Chest pain
- Back pain
- Peripheral edema
- Abdominal pain, dyspepsia, gastroenteritis, diarrhea
Use in pregnancy
Use in Pregnancy: Olmesartan + Hydrochlorothiazide is highly unsafe during pregnancy; definite evidence of severe fetal harm. Do not use.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Periodically measure serum electrolytes (hypokalemia, hyponatremia)
- Hyperuricemia may occur
- Caution in impaired renal function
- Can cause fetal harm in pregnancy
Overdose effects
Overdose - Olmesartan: Hypotension and tachycardia; Hydrochlorothiazide: Electrolyte depletion (hypokalemia, hypochloremia, dehydration); supportive treatment.
Storage conditions
Store in a cool and dry place, protect from light and moisture; keep out of reach of children.