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At a glance

Adapalene 0.1% Topical is a retinoid gel used for the treatment of mild to moderate acne vulgaris. It normalizes skin cell differentiation, unclogs pores and prevents new acne formation.

Indications

Mild to moderate acne vulgaris.

Pharmacology

Adapalene is a retinoid that binds to specific retinoic acid nuclear receptors, normalizing follicular epithelial cell differentiation and reducing microcomedone formation. It acts as a modulator of cellular differentiation, keratinization and inflammatory processes.

Dosage

Adults and children (12 years and older):

  • Apply a pea-sized amount of gel sparingly to the entire face once daily at bedtime
  • Cleanse the face with a mild cleanser and pat dry before application
  • Avoid contact with eyes, lips and mucous membranes
Side effects

Common side effects (during the first 2-4 weeks):

  • Erythema (skin redness)
  • Dry skin
  • Skin peeling
  • Skin burning/stinging
  • Itching

These side effects are usually temporary and decrease with continued use.

Use in pregnancy

Pregnancy Category: C. No adequate controlled studies in pregnant women. Animal studies have shown harmful effects on the fetus. Use only if potential benefit justifies risk.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Avoid exposure to sunlight and artificial UV light (skin becomes more sensitive)
  • Use non-comedogenic sunscreen and protective clothing when sun exposure cannot be avoided
  • Do not apply to broken, sunburnt or eczematous skin
  • Use with caution with preparations containing sulfur, resorcinol, or salicylic acid
  • Avoid contact with eyes, lips and nostrils
  • Do not undergo cosmetic procedures during treatment
  • Consult your doctor if pregnant, planning pregnancy or breastfeeding
Overdose effects

Topical overdose is unlikely; excessive application may increase skin irritation and redness.

Storage conditions

Store below 25°C in a cool and dry place, protected from light. Keep out of reach of children.

Adapalene 0.1% Topical — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.