Plasmex IV
6%+0.9%Rx৳ 654/unit
Pack: ৳ 654
৳ 654/unit
Pack: ৳ 654
At a glance
Poly (0-2-hydroxyethyl) starch 60g + Sodium Chloride is a colloidal solution volume expander used for prophylaxis of hypovolemia and shock, surgery (hemorrhagic shock), injuries (traumatic shock), burns, and therapeutic dilution of blood.
Indications
- Prophylaxis of hypovolemia and shock
- Surgery (hemorrhagic shock)
- Injuries (traumatic shock)
- Burns
- Therapeutic dilution of blood
Pharmacology
The colloidal solution containing hydroxyethyl starch restores plasma volume by increasing intravascular oncotic pressure. It reduces blood viscosity and improves microcirculation. Sodium chloride maintains electrolyte balance.
Dosage
Adult Dose (IV):
- Up to 50 mL/kg body weight per day (equivalent to 3 g hydroxyethyl starch and 7.7 mEq sodium/kg)
- Up to 3500 mL for a 70 kg patient
Pediatric Dose (IV):
- Newborns & <2 years: Mean dose 16 mL/kg
- 2-12 years: Mean dose 36 mL/kg
- Give initial 10-20 mL by slow IV infusion and monitor for anaphylactoid reaction
Side effects
Side Effects (<10%):
- Immune system disorders (rare): Anaphylactoid reactions (mild influenza-like symptoms, bradycardia, tachycardia, bronchospasm, non-cardiac pulmonary edema)
- Skin and subcutaneous tissue disorders (common, dose-dependent): Prolonged administration of high doses may cause pruritus (itching)
Use in pregnancy
Use in Pregnancy: Safety unknown; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Anaphylactoid reactions may occur; if hypersensitivity occurs, discontinue immediately
- Regularly assess fluid status and infusion rate (especially in cardiac insufficiency or severe kidney dysfunction)
- Caution in severe liver disease or severe bleeding disorders
- Contraindicated in renal failure with oliguria or anuria
Overdose effects
Overdose may cause fluid overload, pulmonary edema, heart failure; treatment: stop infusion, diuretics, symptomatic supportive care.
Storage conditions
Store in a cool and dry place; keep out of reach of children.