Ramdex
0.1%+0.5%Rx৳ 70.21/unit
Pack: ৳ 70.21
৳ 70.21/unit
Pack: ৳ 70.21
At a glance
Chloramphenicol 0.5% + Dexamethasone 0.1% Eye/Ear drop is a combination medicine used to treat bacterial infections of the eye or ear.
Indications
- Acute purulent conjunctivitis
- Corneal inflammation and ulceration
- Keratitis disciformis
- Post-herpetic keratitis
- Allergic conjunctivitis and blepharitis
- Acute and chronic iritis
- Chronic anterior uveitis
- Corneal injury
- Post-operative inflammation
- Otitis externa, Otitis media
- Chronic suppurative otitis media
Pharmacology
Dexamethasone is a glucocorticoid. It has an anti-inflammatory and anti-allergic action. It is used topically in the treatment of inflammatory conditions of the anterior segment of the eye. Dexamethasone is absorbed rapidly after oral administration with a half-life of about 190 minutes. Sufficient absorption may occur after topical application to the skin and eye to produce systemic effects.
Chloramphenicol is a broad spectrum bacteriostatic antibiotic active against a wide variety of gram-negative and gram-positive organisms. Chloramphenicol exerts its antibacterial effect by binding to bacterial ribosomes and inhibiting bacterial protein synthesis at an early stage.
Dosage
Eye (Bacterial Conjunctivitis): 1-2 drops every 2 hours for 2 days, then 1-2 drops every 4 hours for the next 5 days.
Eye (Corneal Ulcers): 2 drops every 15 minutes for first 6 hours, then 2 drops every 30 minutes for remainder of first day; 2 drops hourly on 2nd day; 2 drops every 4 hours on days 3-14.
Ear: 2-3 drops every 2-3 hours initially; frequency decreased gradually as clinical signs improve.
Side effects
Common Side Effects:
- Application site irritation
- Burning sensation
- Stinging
- Redness
- Itching
- Conjunctivitis
- Foreign body sensation
- Photophobia
- Blurred vision
- Dryness
- Eye pain
Serious Side Effects: Elevated intraocular pressure, glaucoma, optic nerve damage, posterior subcapsular cataract.
Use in pregnancy
[CONSULT YOUR DOCTOR] Chloramphenicol 0.5% + Dexamethasone 0.1% Eye/Ear drop may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Precautions & warnings
- [UNSAFE] Chloramphenicol 0.5% + Dexamethasone 0.1% Eye/Ear drop may cause side effects which could affect your ability to drive. Dizziness (vertigo), changes in eyesight or muscle weakness may affect your driving ability.
- Prolonged corticosteroid use may result in posterior subcapsular cataract formation and glaucoma with optic nerve damage. Intraocular pressure monitoring is needed.
- Prolonged antibiotic use may result in overgrowth of non-susceptible organisms.
- Do not use after 30 days of first opening.
Overdose effects
Information on overdosage is not available. Consult a physician if overdose is suspected.
Storage conditions
Keep in a cool and dry place, away from light & keep out of the reach of children. Do not use after 30 days of first opening.