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At a glance

Aluminium Hydroxide is an antacid used to neutralize excess stomach acid and treat heartburn, indigestion, gastric hyperacidity and peptic ulcer disease.

Indications

Heartburn, indigestion (dyspepsia), gastric hyperacidity, peptic ulcer disease, hyperphosphataemia in chronic renal failure.

Pharmacology

Aluminium hydroxide reacts with gastric hydrochloric acid to form aluminium chloride and water, reducing gastric acidity. It also binds to phosphate in the intestine, reducing phosphate absorption, which helps control hyperphosphataemia in chronic renal failure patients.

Dosage

Adults (Antacid):

  • Up to 1 g daily (usually with meals or as needed)

Hyperphosphataemia in Chronic Renal Failure:

  • Dose adjusted to individual patient requirement
  • Up to 10 g/day in divided doses with meals
  • Maximum dose: 10 g daily in divided doses
Side effects

Common side effects: Constipation (most common side effect of aluminium hydroxide).

Serious (rare): Intestinal obstruction (with large doses), phosphate depletion (with prolonged or high-dose use), hypophosphataemia, osteomalacia (with long-term use).

Use in pregnancy

There is insufficient information on the use of aluminium hydroxide during pregnancy. Use only if clearly needed with medical advice.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in chronic renal impairment (risk of aluminium accumulation)
  • Caution in congestive heart failure, oedema, cirrhosis, and low sodium diets
  • Caution in patients with recent gastrointestinal haemorrhage
  • Maintain 2-3 hour gap with other medications (to avoid absorption interference)
  • Caution during pregnancy and lactation
Overdose effects

Overdose symptoms: severe constipation, intestinal obstruction, phosphate depletion. Treatment: drug discontinuation and symptomatic measures.

Storage conditions

Store in a cool and dry place, protected from light. Keep out of reach of children.

Aluminium Hydroxide — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.