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Company•Renata Limited

Streptomycin

1gm/vialRx
Generic: Streptomycin

৳ 9.19/unit

Pack: ৳ 9.19

Injection1gm vial
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At a glance

Streptomycin is an aminoglycoside antibiotic used for tuberculosis, bacterial endocarditis, plague, tularemia, and brucellosis. It exhibits bactericidal activity by inhibiting bacterial protein synthesis.

Indications
  • Tuberculosis
  • Bacterial endocarditis
  • Plague
  • Tularemia
  • Brucellosis
  • Bacteremia, meningitis, pneumonia
  • Urinary tract infections
Pharmacology

Streptomycin binds to the bacterial 30S ribosomal subunit, inhibiting the initiation step of protein synthesis, preventing bacterial growth and spread. It is effective against a broad range of bacteria, including Mycobacterium tuberculosis.

Dosage

Adult Dose (IM):

  • Tuberculosis: 15 mg/kg/day (single dose); max 1 g/day
  • Tuberculosis (intermittent): 25-30 mg/kg 2-3 times weekly
  • Bacterial endocarditis: 1 g twice daily (streptococcal – 1 week; enterococcal – 2 weeks), then 500 mg twice daily
  • Plague: 2 g/day in 2 divided doses for 10 days
  • Tularemia: 1-2 g/day in divided doses for 7-14 days

Pediatric Dose (IM):

  • Tuberculosis: 20-40 mg/kg/day; max 1 g/day
  • Severe infections: 20-30 mg/kg/day; max 1 g/day
Side effects

Side Effects:

  • Neurotoxic reactions (vestibular and cochlear dysfunction, optic nerve dysfunction, peripheral neuritis)
  • Facial paresthesia
  • Rash, fever, angioneurotic edema
  • Azotemia, leukopenia, thrombocytopenia
Use in pregnancy

Use in Pregnancy: Adequate information not available; use only if clearly needed; consult your doctor.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in neuromuscular disorders (myasthenia gravis), pre-existing vertigo, or hearing loss
  • Caution in renal impairment, elderly, children
  • Caution in pregnancy and lactation
  • Monitor renal and auditory function
Overdose effects

Overdose may cause neurotoxicity, nephrotoxicity, and neuromuscular blockade; provide symptomatic and supportive treatment; hemodialysis is effective.

Storage conditions

Store in a cool and dry place, protected from light; keep out of reach of children.

Streptomycin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.