oshudhkosh

T-Zol500mg

Rx
Generic:
Tinidazole
Dosage form:
Tablet
Pack size:
Tablet

৳ 2.77/unit

Pack: ৳ 2.77

At a glance

Tinidazole — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Tinidazole is an antibiotic medicine that helps your body fight infections caused by bacteria and parasites. It is used to treat infections of the liver, stomach, intestines, vagina, brain, heart, lungs, and skin. Tinidazole is also used in the treatment of dental infections, leg ulcers and pressure sores. This medicine should be taken with food, at the same time each day to get the most benefit. The amount you are advised will depend on what you are being treated for and how bad it is, but you should take this antibiotic exactly as prescribed by your doctor. Your symptoms may get better after a short time but do not stop taking it until you have finished a full course of treatment, even if you feel well. If you stop taking it early, some bacteria may survive, and the infection may come back. Do not drink any alcohol while taking this medicine and for some days after stopping it. Otherwise, you may get unpleasant side effects like nausea, vomiting and stomach pain. The most common side effects of this medicine are headache, dryness in mouth, nausea, and a slight metallic taste in the mouth. These are usually mild but let your doctor know if they bother you or last more than a few days. You can try using sugarless candies or lozenges to overcome any dryness or metallic taste in the mouth. Before using this medicine, inform your doctor if you are allergic to any medicine or have any kidney or liver problems or any disease of the nervous system. Your doctor may change the dose or prescribe a different medicine. This medicine should not be taken if you are pregnant or breastfeeding unless it is absolutely necessary and prescribed by your doctor. Tinidazole is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging their DNA.

Indications

• Bacterial infections • Parasitic infections

Mechanism of action

Tinidazole, a 5-nitroimidazole derivative w/ antimicrobial actions similar to metronidazole, is active against both protozoa (e.g. Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia) and obligate anaerobic bacteria. It damages DNA strands or inhibits DNA synthesis in microorganism.

Dosage

Adult Dose: Oral Bacterial vaginosis Adult: 2 g as single dose. May also be given as 2 g for 2 consecutive days or 1 g daily for 5 days. Anaerobic bacterial infections Adult: 2 g on the 1st day, followed by 1 g daily or 500 mg bid for 5-6 days. Prophylaxis of postoperative anaerobic bacterial infections Adult: 2 g as single dose 12 hr before surgery. Eradication of H. pylori associated with peptic ulcer disease Adult: 500 mg bid, given w/ clarithromycin and omeprazole for 7 days. Intestinal amoebiasis Adult: 2 g daily for 2 or 3 days. Hepatic amoebiasis Adult: 1.5-2 g daily for 3-6 days. Giardiasis Adult: 2 g as single dose. Trichomoniasis; Acute necrotising ulcerative gingivitis Adult: 2 g as single dose. In trichomoniasis, sexual partners should be treated at the same time. Intravenous IV Susceptible infections Initial: Infuse 800 mg, followed by 800 mg/day or 400 mg twice daily till PO can be given. Surgical prophylaxis 1.6 g as single infusion pre-op. Child Dose: Oral Intestinal amoebiasis Child: >3 yr 50-60 mg/kg daily for 3 consecutive days. Max: 2 g/day. Hepatic amoebiasis Child: >3 yr 50-60 mg/kg daily for 5 days. Max: 2 g/day. Giardiasis Child: >3 yr 50-75 mg/kg as single dose, repeat if necessary. Max: 2 g/day. Renal Dose: Renal impairment: Haemodialysis: Additional dose equal to half the usual dose at the end of haemodialysis.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tinidazole is to be taken with food.

Missed dose

If you miss a dose of Tinidazole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Common: • Headache • Dryness in mouth • Nausea • Metallic taste

Precautions & warnings

[UNSAFE] Tinidazole may cause side effects which could affect your ability to drive. Tinidazole may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability. Tinidazole treats infections caused by bacteria and parasites. It may also be used to prevent infections following surgery. Always take the complete course of treatment, as advised by your doctor, even if you feel better. It may cause side effects like nausea, stomach upset, and a metallic taste in the mouth. Tinidazole used in a high dose or for a prolonged time increases the risk of side effects such as nerve damage. Take it only as prescribed by your doctor. Do not drink alcohol during or for 2-3 days after treatment with this medicine. You may develop nausea, vomiting, flushing and headache. Inform your doctor if you have liver disease. Your dose may need to be adjusted in severe liver disease.

Contraindications

Blood dyscrasias, organic neurologic disorders, hypersensitivity to 5-nitroimidazole derivatives, porphyria. Lactation, pregnancy (1st trimester).

Drug interactions

May potentiate the effects of oral anticoagulants resulting to prolonged prothrombin time.

Food interactions

[UNSAFE] Consuming alcohol while taking Tinidazole may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Use in pregnancy

[CONSULT YOUR DOCTOR] Tinidazole may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[CAUTION] Tinidazole should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body. If a single dose of Tinidazole is used, it is recommended to hold breastfeeding for 12-24 hours to allow the removal of the drug.

Renal / hepatic impairment

[SAFE IF PRESCRIBED] Tinidazole is safe to use in patients with kidney disease. No dose adjustment of Tinidazole is recommended. [SAFE IF PRESCRIBED] Tinidazole is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Tinidazole may not be needed in these patients. Please consult your doctor.

Common questions

I have a history of recurring yeast and bacterial vaginosis infections. Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days Scar on face due to bacterial infections Pic is not clear, plz visit for proper opinion My child verry high cough and fever in cold sesion try to much doctor but result is no . It's will be countiue cough and fever it's good to be only antiboitic Antibiotics are required if bacterial infections. Consult child specialist What are use mega-cv dry syrup Child are not drinking milk Mega CV is an antibiotic used to treat bacterial infections I suffering from bacterial infections in my shaving area or too much acne problem. Fudic cream twice a day

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.