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At a glance

Isopropamide + Trifluoperazine combination is used for the treatment of Irritable Bowel Syndrome (IBS), relieving abdominal pain, cramping, bloating, and diarrhea or constipation.

Indications
  • Irritable Bowel Syndrome (IBS)
Pharmacology

Isopropamide is an anticholinergic which works by blocking the binding of acetylcholine to its receptor in nerve cells, relaxing smooth muscles in the digestive tract and decreasing spasms. Trifluoperazine is a typical antipsychotic that works by blocking the action of dopamine in the brain. This combination relieves abdominal pain and cramps.

Dosage

Adult Dose (Oral):

  • Take in the dose and duration as advised by your doctor
  • May be taken with or without food

Child Dose: No specific data; use as directed by physician

Side effects

Common Side Effects:

  • Nausea
  • Constipation
  • Dryness in mouth
  • Weight gain
  • Sleepiness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Dizziness
  • Blurred vision
  • Difficulty in urination
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies have shown harmful effects; doctor will weigh benefits and risks.

Precautions & warnings

Precautions:

  • Isopropamide + Trifluoperazine may affect your ability to drive (dizziness, drowsiness, blurred vision)
  • Avoid alcohol (may increase drowsiness)
  • Lifestyle modifications (fiber-rich diet, avoiding trigger foods, increasing fluid intake, regular exercise) can help
  • Inform doctor if you have kidney or liver disease
  • Inform doctor if pregnant, planning pregnancy or breastfeeding
Overdose effects

No information on overdose; do not exceed the recommended dose.

Storage conditions

Store in a cool and dry place, protected from light; keep out of reach of children.

Isopropamide + Trifluoperazine — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.