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At a glance

Dorzolamide 2% + Timolol 0.5% Eye prep is used to reduce pressure in the eyes. This pressure can be caused by or lead to glaucoma. It works by decreasing the amount of fluid inside the eye.

Indications
  • Glaucoma
Pharmacology

Timolol maleate, a nonselective beta-adrenergic blocker, reduces aqueous humor formation. Dorzolamide, a carbonic anhydrase inhibitor, decreases aqueous humor secretion by inhibiting carbonic anhydrase in the ciliary processes.

Dosage

Adult Dose: 1 drop in the affected eye twice daily.

Child Dose (over 2 years): 1 drop in the affected eye twice daily.

Renal Dose: CrCl <30: Not recommended.

Side effects

Common Side Effects:

  • Headache
  • Nausea
  • Fatigue
  • Burning sensation
  • Bitter taste
Use in pregnancy

Dorzolamide 2% + Timolol 0.5% Eye prep may be unsafe during pregnancy. Animal studies have shown harmful effects. Doctor will weigh benefits and risks.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Lowers high eye pressure and reduces risk of vision loss.
  • Apply pressure on the corner of the eye for 1 minute after instilling the drop.
  • Do not touch the dropper tip to any surface or eye.
  • Remove contact lenses before use and wait 15 minutes before re-inserting.
Overdose effects

Limited information on overdose. Overdose is generally not toxic.

Storage conditions

Store in a cool & dry place, protect from light. Do not use longer than one month after first opening. Keep out of reach of children.

Dorzolamide 2% + Timolol 0.5% Eye prep — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.