Tobasol300mg/5ml
Rx- Generic:
- Tobramycin Sulphate
- Company:
- Beximco Pharmaceuticals Ltd.
- Dosage form:
- Respirator Solution
- Pack size:
- 1's pack
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৳ 100/unit
Pack: ৳ 100
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At a glance
Tobramycin Sulphate is an aminoglycoside antibiotic used via inhalation for managing Pseudomonas aeruginosa infection in cystic fibrosis patients. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
Indications
- Management of Pseudomonas aeruginosa in patients with cystic fibrosis
Dosage
Adult Dose (Inhalation):
- 300 mg ampoule every 12 hours inhaled from a suitable nebulizer for 28 days, then stop for 28 days; repeat in cycles of 28 days as needed
Pediatric Dose (>6 years):
- Same as adult dose
Side effects
Common Side Effects (>10%):
- Voice alteration (12.8%)
1-10%:
- Myalgia (4.7%)
- Laryngitis (4.3%)
- Tinnitus (3%)
- Epistaxis (3%)
Precautions & warnings
- Caution in pre-existing renal and auditory/vestibular impairment
- Caution in dehydration, neuromuscular blockade, myasthenia gravis, parkinsonism
- Caution in neonates, elderly, and lactation
- Dose adjustment needed in renal impairment
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.