Zybex SR150mg
Rx- Generic:
- Bupropion Hydrochloride
- Company:
- Beximco Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 10/unit
Pack: ৳ 10
At a glance
Bupropion Hydrochloride — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Bupropion Hydrochloride is a prescription medicine used in the treatment of depression and smoking addiction. This medicine helps by increasing the level of chemical messengers in the brain that relax the nerves and have a calming effect on the brain. Bupropion Hydrochloride may be taken with or without food. It is advised to take this medicine at a fixed time each day. You should never skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly as it may worsen your symptoms. Some common side effects of this medicine include insomnia (difficulty sleeping), allergic reaction, impaired concentration, sweating, headache, nausea, vomiting, and dry mouth. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus. Moreover, most of the side effects are immediate and often go away with time. Please consult your doctor if these bother you or do not go away. Before taking this medicine it is important to inform your doctor if you have any history of seizure or if you drink alcohol. Inform your doctor if you develop any unusual changes in mood or if you have any suicidal thoughts. Bupropion Hydrochloride works in depression by increasing the levels of chemical messengers in the brain that helps in regulating mood. The mechanism underlying its use in smoking addiction are not fully understood.
Indications
• Depression • Smoking addiction
Mechanism of action
Bupropion HCl is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotinin and dopamine. The mechanism by which it aids in smoking cessation is presumed to be mediated by its noradrenergic and/or dopaminergic actions.
Dosage
Adult Dose: Oral Smoking cessation Adult: Modified-release preparation: Initially, 150 mg once daily for 6 days then increased to 150 mg bid. Period of treatment: 7-12 wk. To discontinue treatment if abstinence is not achieved by 7th wk. Max: 300 mg/day. Elderly: 150 mg/day. Hepatic impairment: Mild to moderate: 150 mg once daily. Severe hepatic cirrhosis: Contraindicated. Depression Adult: Initially, 100 mg bid increased to 100 mg tid after 3 days if necessary. Increased further to 150 mg tid if no improvement has been observed after several wk of therapy. Max: 150 mg tid. As a modified-release preparation: 150 mg once daily in the morning, increased to 150 mg bid after 3 days if necessary, may further increase to 200 mg bid after several wk if needed. Max: 450 mg as a single dose. Elderly: As immediate-release tab: Initially, 37.5 mg bid. As sustained-release tab: Initially, 100 mg daily. Dose may be increased by 37.5-100 mg every 3-4 days as tolerated. Max: 300 mg daily in divided doses. Hepatic impairment: Mild to moderate: Reduce dose or dosing frequency. Severe: As immediate-release preparation: Max: 75 mg once daily. As modified-release preparation: Max: 100 mg once daily or 150 mg every other day. Renal Dose: Renal impairment: Use caution; consider dose reduction
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bupropion Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Bupropion Hydrochloride, skip it and continue with your normal schedule. Do not double the dose.
Side effects
Common: • Insomnia (difficulty in sleeping) • Allergic reaction • Impaired concentration • Sweating • Headache • Nausea • Vomiting • Dizziness • Dryness in mouth • Taste change • Abdominal pain • Agitation • Anxiety • Fever • Constipation • Tremor
Precautions & warnings
[UNSAFE] Bupropion Hydrochloride may cause side effects which could affect your ability to drive. Bupropion Hydrochloride may cause dizziness or light-headedness, may affect your concentration and judgement. This may affect your driving ability. You have been prescribed Bupron XL 150 Tablet for the treatment of depression. It can also help you quit smoking. Take it in the morning to avoid difficulty sleeping later that night. It causes fewer side effects as compared to other anti-depression medications. Stop taking Bupron XL 150 Tablet and inform your doctor if you notice sudden mood and behavior changes or develop suicidal thoughts. Inform your doctor if you have a history of seizure disorder, eating disorder, or if you drink alcohol.
Contraindications
It is contraindicated in patients with a seizure disorder. Bupropion Hydrochloride is contraindicated in patients treated with other medications that contain Bupropion because the incidence of seizure is dose dependent. Bupropion may induce seizure and consequently its use is contraindicated in patients with epilepsy. The drug is also contraindicated in patients with a current or prior diagnosis of bulimia or anorexia nervosa because of a higher incidence of seizures noted in such patients treated for bulimia with Bupropion Hydrochloride. The concurrent administration of Bupropion Hydrochloride and a monoamine oxidase (MAO) inhibitor is contraindicated. At least 14 days should elapse between discontinuation of MAO inhibitor and initiation of treatment with Bupropion Hydrochloride. Bupropion Hydrochloride is contraindicated in patients who have shown an allergic response to Bupropion or the other ingredients that make up Bupropion Hydrochloride.
Drug interactions
Neuroleptics, lithium and TCAs, benzodiazepine, alcohol, drugs that lower seizure threshold. Increased risk of side effects when co-admin with levodopa. Reduced hepatic clearance with fluoxetine. Caution when administering with agents that will affect hepatic drug metabolizing enzymes. Increased risk of toxicity when used with ritonavir. Potentially Fatal: Concurrent use with MAO inhibitors may cause acute toxicity symptoms and increased risk of fatality.
Food interactions
[UNSAFE] Bupropion Hydrochloride may cause excessive drowsiness with alcohol.
Use in pregnancy
[CONSULT YOUR DOCTOR] Bupropion Hydrochloride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Bupropion Hydrochloride is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CAUTION] Bupropion Hydrochloride should be used with caution in patients with kidney disease. Dose adjustment of Bupropion Hydrochloride may be needed. Please consult your doctor. [CAUTION] Bupropion Hydrochloride should be used with caution in patients with liver disease. Dose adjustment of Bupropion Hydrochloride may be needed. Please consult your doctor. Caution is advised for the use of Bupropion Hydrochloride in these patients with close monitoring from a doctor for any possible side effects.
Common questions
Sleeping problem in night taken medicine etizolam 5mg. Inzofresh 10 mg AND ALSO TAKEN MEDICINE FOR ANTI SMOKING IS BUPRON XL BD 150 &THEALIFE BD Sleep disturbance is often a manifestation of underlying psychological disorder. Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions. Dear Sir can i take stablon, Duzela 20mg & bupron xl 150 all medicine together Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. If your psychiatrist has prescribed all medicines, he must have analysed the need for it. anxiety i m suffering from.taking bupron sr 150 n etizola0.5 mg n still anxiety continues Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. Treatment for Recurrent Depressive Disorder , psychotic disorders, Bipolar Affective Disorder and OCD usually lasts for much longer.To monitor any potential side effects and to take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions. i m taking bupron xl 150 n etizola 0.5 . still anxiety comes. pls help everything fine with thismedicine but anxiety cant be controlled Dear PATIENT you to consult the same doctor for further improvement I'm having depression, anxiety and IBS for 2 years. I consulted a psychiatrist on lybrate app. He prescribed me Bupron XL 150, Lonazep 0.5mg and I'm taking mebeverine for IBS. I've been taking this for 2 weeks and I feel awesome how long do I need to take this medication? Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions. I was diagnosed with endogenous depression and currently taking Bupron XL 150 BD and I also started having low libido and no erections. I am taking Nano Leo cap 1 daily for last two months. But there is no increase in libido and erections. Please suggest what shud be treatment My Testosterone total is 1.72 ng/ml. range 2.41-8.7 pls suggest Medicines are prescribed after clinical examination. This portal is to guide you regarding your problems and clarify doubts. Please see a psychiatrist for treatment. I was on librex 1/2 1/2 for IBS. Now doctor started bupron xl 150 in morning and ventab dxt 50 at night. I am not confined now. Are these tablets safe? I feel councilling will be much better for me. Should I go for that? I feel my doctor is not so efficient. Kindly advice. Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you. sir i have effective in depression illnes I have take in 5yrs continuing in tablat so any other threphy in its not tablat sir I am taking tablat below1 Nitrosun5mg, 2,Bupron sr 150mg,3,Duzela30mg, 4,Ridazin10mg Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.